PPIF and SERPINB5

Number of citations of the paper that reports this interaction (PubMedID 16049007)
0

Data Source:
BioGRID (two hybrid)

		PPIF	SERPINB5
Description		peptidylprolyl isomerase F	serpin family B member 5
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Permeability Transition Pore Complex Mitochondrial Matrix Membrane	Cornified Envelope Extracellular Region Extracellular Space Cytoplasm Sarcoplasm
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Isomerase Activity	Serine-type Endopeptidase Inhibitor Activity Protein Binding
	Biological Process	Response To Ischemia Protein Folding Apoptotic Process Response To Oxidative Stress Mitochondrion Organization Apoptotic Mitochondrial Changes Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Mitochondrial Depolarization Muscle Structure Development Necroptotic Process Cellular Response To Hydrogen Peroxide Cellular Response To Arsenic-containing Substance Cellular Response To Calcium Ion Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Oxidative Phosphorylation Skeletal Muscle Fiber Differentiation Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Morphogenesis Of An Epithelium Extracellular Matrix Organization Regulation Of Epithelial Cell Proliferation Prostate Gland Morphogenesis
Pathways
Drugs		Cyclosporine Proline Triglyme Coumarin 120	S,S-(2-Hydroxyethyl)Thiocysteine
Diseases
GWAS		Appendicular lean mass ( 33097823) Blood protein levels ( 30072576) Height ( 20881960 31562340) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean platelet volume ( 32888494) Metabolite levels ( 23823483) Triglyceride levels ( 32203549)	Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule) ( 24025145)
Interacting Genes		19 interacting genes: ABI2 AGTRAP ARFIP2 BANP CIDEB CMTM5 FAM25A FAM25C FAM25G FKBP7 MAGEA11 MUC1 PRB3 SERPINB5 SLC25A4 SYP SYPL1 VDAC1 YIF1A	26 interacting genes: AKT1 ATIC BASP1 BCAR3 CASP8 COL1A2 EEF1A1 ESR1 GOLGA4 GSTO1 HDAC1 HSP90AA1 HSP90AB1 HSPA5 KRAS LRRFIP1 MDH1 MT1H PALB2 PPIF PTBP1 SMAD4 TBP TKT UCHL5 XRCC3
Entrez ID		10105	5268
HPRD ID		06839	01111
Ensembl ID		ENSG00000108179	ENSG00000206075
Uniprot IDs		P30405	P36952
PDB IDs		2BIT 2BIU 2Z6W 3QYU 3R49 3R4G 3R54 3R56 3R57 3R59 3RCF 3RCG 3RCI 3RCK 3RCL 3RD9 3RDA 3RDB 3RDC 4J58 4J59 4J5A 4J5B 4J5C 4J5D 4J5E 4O8H 4O8I 4XNC 4ZSC 4ZSD 5A0E 5CBT 5CBU 5CBV 5CBW 5CCN 5CCQ 5CCR 5CCS 6R8L 6R8O 6R8W 6R9S 6R9U 6R9X 6RA1 6Y3E 6YBM 7OGI 7PMT 7R2H 7R2I 7R2J 7R2L 7TGS 7TGT 7TGU 7TGV 7TH1 7TH6 7TH7 7THC 7THD 7THF 7ZDN 8EJX 8UC4 8UC5	1WZ9 1XQG 1XQJ 1XU8
Enriched GO Terms of Interacting Partners?		Mitochondrial Permeability Transition Pore Complex	Nitric-oxide Synthase Regulator Activity Protein-containing Complex Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process Cytoplasm Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Apoptotic Process Regulation Of Nitric Oxide Metabolic Process Regulation Of Programmed Cell Death Negative Regulation Of Programmed Cell Death Kinase Binding Regulation Of Protein Catabolic Process Cytosol Extracellular Exosome TFIIB-class Transcription Factor Binding Telomere Maintenance COP9 Signalosome ATP-dependent Protein Folding Chaperone Animal Organ Development Nucleobase-containing Compound Metabolic Process Negative Regulation Of Apoptotic Process Telomerase Holoenzyme Complex Assembly Telomere Organization Protein Homodimerization Activity Positive Regulation Of Signal Transduction Brainstem Development Transcription Corepressor Binding Dendritic Growth Cone TPR Domain Binding Regulation Of Intracellular Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Folding Chaperone Negative Regulation Of Intracellular Signal Transduction PERK-mediated Unfolded Protein Response Maintenance Of Protein Localization In Endoplasmic Reticulum Negative Regulation Of PERK-mediated Unfolded Protein Response Striated Muscle Cell Differentiation Positive Regulation Of Cell Communication Regulation Of Signal Transduction Positive Regulation Of Signaling Developmental Process Negative Regulation Of Muscle Cell Differentiation Macromolecule Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Striated Muscle Contraction Regulation Of Protein Ubiquitination Intracellular Signaling Cassette Positive Regulation Of Biosynthetic Process Regulation Of Growth Positive Regulation Of Cell Differentiation
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