SLC25A4

Name	solute carrier family 25 member 4
Structure	No pdb structure
Interactors	7 interactors: AR BAX NFKBIA NR3C1 PPID PPIF PRKCE
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Permeability Transition Pore Complex Plasma Membrane Membrane Mitochondrial Membrane
	Molecular Function	ATP:ADP Antiporter Activity Protein Binding Proton Transmembrane Transporter Activity Adenine Transmembrane Transporter Activity Antiporter Activity Oxidative Phosphorylation Uncoupler Activity
	Biological Process	Generation Of Precursor Metabolites And Energy Apoptotic Mitochondrial Changes Adenine Transport ADP Transport Regulation Of Mitochondrial Membrane Permeability Transmembrane Transport Negative Regulation Of Necroptotic Process Mitochondrial ADP Transmembrane Transport Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitophagy Proton Transmembrane Transport Mitochondrial ATP Transmembrane Transport Adaptive Thermogenesis
Pathways	Mitochondrial protein import Mitochondrial protein import Mitochondrial Uncoupling Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs	ATP Clodronic acid Etidronic acid [3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium Carboxyatractyloside Tetrastearoyl cardiolipin Di-Stearoyl-3-Sn-Phosphatidylcholine
GWAS	No GWAS studies recorded
Entrez ID	291
HPRD ID	00058
Ensembl ID	ENSG00000151729
Uniprot IDs	A0A0S2Z3H3 P12235
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Mitochondrial Permeability Transition Pore Complex Estrogen Response Element Binding Apoptotic Process Programmed Cell Death Cell Death Cyclosporin A Binding Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Regulation Of Cellular Localization Steroid Binding Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Signaling Pathway Response To Ketone Intracellular Receptor Signaling Pathway Positive Regulation Of Membrane Permeability Peptidyl-prolyl Cis-trans Isomerase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Metabolic Process Regulation Of Transport Regulation Of Monoatomic Cation Transmembrane Transport Hsp90 Protein Binding Toll-like Receptor 4 Signaling Pathway Regulation Of Release Of Cytochrome C From Mitochondria Response To Lipid Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Surface Toll-like Receptor Signaling Pathway Regulation Of Monoatomic Ion Transmembrane Transport Hsp70 Protein Binding Nuclear Receptor Activity B Cell Receptor Signaling Pathway Cellular Response To Oxygen-containing Compound Cell Surface Pattern Recognition Receptor Signaling Pathway Intracellular Signal Transduction Positive Regulation Of MiRNA Transcription Regulation Of Mitochondrial Membrane Permeability Regulation Of Protein Localization Lipid Binding Cellular Response To Hormone Stimulus Positive Regulation Of MiRNA Metabolic Process Immune Response-activating Signaling Pathway Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Mitochondrial Changes Enzyme Binding Prostate Induction Regulation Of Apoptotic Signaling Pathway Regulation Of MiRNA Transcription Regulation Of Intracellular Signal Transduction