CCDC113 and SMYD1

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		CCDC113	SMYD1
Gene Name		coiled-coil domain containing 113	SET and MYND domain containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Centriolar Satellite Protein Complex	Nucleus Cytoplasm
	Molecular Function	Protein Binding	DNA Binding Transcription Corepressor Activity Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding
	Biological Process	Cilium Assembly	Chromatin Remodeling Transcription, DNA-templated Heart Development Positive Regulation Of Myotube Differentiation Histone Lysine Methylation Skeletal Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: GIT1 HAP1 IMMT PFN2 SMYD1	19 interactors: ADSS BHLHE40 C11orf16 C11orf53 CCDC113 FAM204A H3F3C HDAC2 HDAC3 HOMEZ LENG8 MYH7B NACA OGDHL RBM4B TTC33 UTP14A WDR77 ZBTB44
Entrez ID		29070	150572
HPRD ID		07121	06025
Ensembl ID		ENSG00000103021	ENSG00000115593
Uniprot IDs		Q9H0I3	E9PHG3 Q5HYE8 Q8NB12
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Regulation Of Cell Projection Assembly Regulation Of Exocytosis Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Cilium Assembly Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Cellular Component Movement Negative Regulation Of Locomotion Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Ruffle Assembly Regulation Of Synaptic Transmission Positive Regulation Of Cellular Component Biogenesis Hypothalamus Cell Differentiation Negative Regulation Of Beta-amyloid Formation Retrograde Axon Cargo Transport Regulation Of Vesicle-mediated Transport Positive Regulation Of Organelle Organization Negative Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Microtubule-based Movement Positive Regulation Of Synaptic Transmission, GABAergic Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Smooth Muscle Cell Migration Mitochondrial Calcium Ion Homeostasis DNA Demethylation Regulation Of Ruffle Assembly Positive Regulation Of Myoblast Differentiation Regulation Of Cell Projection Organization Regulation Of Cell Cycle Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Telomere Maintenance Via Semi-conservative Replication Regulation Of Beta-amyloid Formation Regulation Of Cilium Assembly Nuclear DNA Replication Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Amyloid Precursor Protein Catabolic Process Telomere Maintenance Via Recombination Positive Regulation Of ERBB Signaling Pathway Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Hypothalamus Development Positive Regulation Of Organelle Assembly Positive Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Cell Migration Anterograde Axon Cargo Transport Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Positive Regulation Of ATPase Activity DNA Strand Elongation	Circadian Regulation Of Gene Expression Circadian Rhythm RNA Metabolic Process Rhythmic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone H4 Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Histone H3 Deacetylation Nitrogen Compound Metabolic Process Histone H3-K9 Modification Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Growth Regulation Of Transcription From RNA Polymerase II Promoter Histone Deacetylation Regulation Of Developmental Growth Protein Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Response To Ammonium Ion Regulation Of Striated Muscle Cell Differentiation RNA Biosynthetic Process Regulation Of Circadian Rhythm Maintenance Of Chromatin Silencing 'de Novo' AMP Biosynthetic Process Positive Regulation Of Skeletal Muscle Tissue Growth Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Striated Muscle Tissue Development Regulation Of Gene Expression Response To Abiotic Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development AMP Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Regulation Of Muscle Cell Differentiation Aspartate Metabolic Process Fungiform Papilla Formation Negative Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Cellular Metabolic Process Fungiform Papilla Morphogenesis
Tagcloud ?			adenosylhomocysteine autoinhibited autoinhibition away bend bending cochaperones crevice ctd ctds flexibility helices interdomain intradomain k4 lobed methylate move outwards restricts sinefungin smyd2 smyd3 stabilizes structurally superimposable tetratricopeptide tpr
Tagcloud (Difference) ?			adenosylhomocysteine autoinhibited autoinhibition away bend bending cochaperones crevice ctd ctds flexibility helices interdomain intradomain k4 lobed methylate move outwards restricts sinefungin smyd2 smyd3 stabilizes structurally superimposable tetratricopeptide tpr
Tagcloud (Intersection) ?