FAM133A and CCNL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM133A	CCNL1
Description		family with sequence similarity 133 member A	cyclin L1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Protein Binding	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process		Regulation Of Transcription By RNA Polymerase II Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of Centrosome Cycle Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Adiponectin levels in pregnancy ( 28317342) Adult body size ( 32376654) Alanine aminotransferase levels ( 33547301) Anthropometric traits in newborns ( 23575227) Birth weight ( 20372150 23202124 31453325 31043758 27680694) Birth weight variance ( 31453325) Body fat percentage variance ( 31453325) Body mass index ( 26426971) circulating leptin levels ( 32917775 26833098) circulating leptin levels adjusted for BMI ( 26833098 32917775) Coronary artery disease ( 33020668) Diabetic retinopathy ( 21441570) Eating disorders ( 22911880) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Menarche (age at onset) ( 25231870) Offspring birth weight ( 31043758) PR interval ( 32439900 30046033) Smoking cessation in chronic obstructive pulmonary disease ( 21685187)
Interacting Genes		17 interacting genes: AGPAT3 BEND7 C1orf35 CCNL1 CEP70 CT45A1 H2BC15 MACROH2A1 MACROH2A2 NKAPD1 PRR13 RBMX2 RNF151 SDCBP2 STAC3 THAP1 TRIM23	21 interacting genes: APP APPBP2 C1orf35 CASP8 CDK11A DVL3 FAM133A JMJD6 KRTAP12-2 NKAPD1 PRDM6 PRPF40A RAD51D RNPS1 RSRP1 SORBS3 SREK1IP1 SRSF2 TFIP11 ZRANB1 ZRSR2
Entrez ID		286499	57018
HPRD ID		06562	10814
Ensembl ID		ENSG00000179083	ENSG00000163660
Uniprot IDs		Q8N9E0	Q9UK58
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Barr Body Negative Regulation Of Transcription By RNA Polymerase I Establishment Of Protein Localization To Chromatin Structural Constituent Of Chromatin Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Nucleosome Nucleosome Assembly Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Keratinocyte Differentiation Nucleosome Organization Protein Heterodimerization Activity Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Epidermis Development Regulation Of Keratinocyte Differentiation Protein-DNA Complex Assembly Regulation Of Transcription By RNA Polymerase I Identical Protein Binding Negative Regulation Of Protein Localization To Chromosome, Telomeric Region Regulation Of Epidermal Cell Differentiation ADP-D-ribose Binding Regulation Of NAD Metabolic Process Positive Regulation Of Epithelial Cell Differentiation Regulation Of Epidermis Development Regulation Of RDNA Heterochromatin Formation Positive Regulation Of Endodermal Cell Differentiation Positive Regulation Of Response To Oxidative Stress ADP-D-ribose Modification-dependent Protein Binding Chromatin DNA Binding	RNA Splicing MRNA Processing MRNA Metabolic Process Regulation Of MRNA Processing RNA Processing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Nucleic Acid Binding
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