FAM133A and AGPAT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM133A	AGPAT3
Description		family with sequence similarity 133 member A	1-acylglycerol-3-phosphate O-acyltransferase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Nucleus Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Endomembrane System Membrane
	Molecular Function	Protein Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity Lysophosphatidic Acid Acyltransferase Activity
	Biological Process		Lipid Metabolic Process Phosphatidic Acid Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process
Pathways			Synthesis of PA COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Adverse response to drug ( 30420678) Estimated glomerular filtration rate in diabetes ( 31451708) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377)
Interacting Genes		17 interacting genes: AGPAT3 BEND7 C1orf35 CCNL1 CEP70 CT45A1 H2BC15 MACROH2A1 MACROH2A2 NKAPD1 PRR13 RBMX2 RNF151 SDCBP2 STAC3 THAP1 TRIM23	19 interacting genes: ABHD16A APP AQP6 BNIP2 CREB3 CREB3L1 FAM133A GOLT1A HSD17B11 HSD17B13 MPP1 NKAPD1 SLC10A1 SLC35H1 SLC71A2 SREK1IP1 TMEM14B TMEM167B TMX2
Entrez ID		286499	56894
HPRD ID		06562	10637
Ensembl ID		ENSG00000179083	ENSG00000160216
Uniprot IDs		Q8N9E0	Q9NRZ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Barr Body Negative Regulation Of Transcription By RNA Polymerase I Establishment Of Protein Localization To Chromatin Structural Constituent Of Chromatin Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Nucleosome Nucleosome Assembly Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Keratinocyte Differentiation Nucleosome Organization Protein Heterodimerization Activity Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Epidermis Development Regulation Of Keratinocyte Differentiation Protein-DNA Complex Assembly Regulation Of Transcription By RNA Polymerase I Identical Protein Binding Negative Regulation Of Protein Localization To Chromosome, Telomeric Region Regulation Of Epidermal Cell Differentiation ADP-D-ribose Binding Regulation Of NAD Metabolic Process Positive Regulation Of Epithelial Cell Differentiation Regulation Of Epidermis Development Regulation Of RDNA Heterochromatin Formation Positive Regulation Of Endodermal Cell Differentiation Positive Regulation Of Response To Oxidative Stress ADP-D-ribose Modification-dependent Protein Binding Chromatin DNA Binding	Steroid Dehydrogenase Activity Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Positive Regulation Of Monocyte Chemotaxis Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
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