RPL7L1 and EGR2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RPL7L1	EGR2
Gene Name		ribosomal protein L7-like 1	early growth response 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ribosome	Nucleus Cytoplasm
	Molecular Function	Poly(A) RNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Activating Transcription Factor Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Ligase Activity Ubiquitin Protein Ligase Binding Transcription Regulatory Region DNA Binding Metal Ion Binding HMG Box Domain Binding
	Biological Process		Transcription From RNA Polymerase II Promoter Protein Export From Nucleus Brain Development Peripheral Nervous System Development Learning Or Memory Rhythmic Behavior Motor Neuron Axon Guidance Schwann Cell Differentiation Protein Sumoylation Facial Nerve Structural Organization Rhombomere 3 Formation Rhombomere 5 Formation Regulation Of Ossification Response To Insulin Brain Segmentation Skeletal Muscle Cell Differentiation Myelination Negative Regulation Of Apoptotic Process Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Neuronal Synaptic Plasticity Cellular Response To CAMP Cellular Response To Gonadotropin Stimulus
Pathways			Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			Atopic dermatitis ( 23042114) Ewing sarcoma ( 22327514) Temperament ( 22832960)
Protein-Protein Interactions		2 interactors: EGR2 UBC	16 interactors: ACP5 BPGM HCFC1 HN1L MED31 NAB2 NDUFS2 NFATC1 RBM15B RIMKLB RPL7L1 SOX10 SOX8 SRA1 UBE2I WWP2
Entrez ID		285855	1959
HPRD ID		18000	00551
Ensembl ID		ENSG00000146223	ENSG00000122877
Uniprot IDs		A8K5J5 Q6DKI1	P11161
PDB IDs
Enriched GO Terms of Interacting Partners?		Rhombomere 5 Formation Rhombomere 3 Formation Rhombomere 3 Morphogenesis Rhythmic Process Brain Segmentation Rhombomere 3 Development Rhombomere 5 Development Rhombomere Morphogenesis Protein Modification By Small Protein Conjugation Rhombomere Development Viral Protein Processing Facial Nerve Structural Organization Facial Nerve Morphogenesis Transcription From RNA Polymerase II Promoter Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Rhythmic Behavior Parasympathetic Nervous System Development Anatomical Structure Arrangement Negative Regulation Of Cell Death Notch Receptor Processing Positive Regulation Of Transcription From RNA Polymerase II Promoter Virion Assembly Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Gonadotropin Stimulus Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Protein Sumoylation Glycogen Biosynthetic Process Intracellular Transport Of Virus Motor Neuron Axon Guidance Positive Regulation Of Transcription, DNA-templated Protein Export From Nucleus Cellular Polysaccharide Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Polysaccharide Biosynthetic Process Response To Gonadotropin Autonomic Nervous System Development Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Apoptotic Process Negative Regulation Of ERBB Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To CAMP Intracellular Transport Positive Regulation Of Gene Expression Regulation Of Cell Death Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Cranial Nerve Development	Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Enteric Nervous System Development Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Peripheral Nervous System Development Regulation Of Transcription From RNA Polymerase II Promoter Mesenchymal Cell Development Heterocycle Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Mesenchymal Cell Differentiation Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process RNA Metabolic Process Glial Cell Differentiation Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Mesenchyme Development Viral Process Gene Expression Nucleobase-containing Compound Metabolic Process Autonomic Nervous System Development Cellular Macromolecule Biosynthetic Process Gliogenesis Neural Crest Cell Migration Regulation Of Metabolic Process Stem Cell Development Macromolecule Biosynthetic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Gliogenesis Metabolic Process Positive Regulation Of SUMO Transferase Activity Neural Crest Cell Development Stem Cell Differentiation Oligodendrocyte Differentiation Neural Crest Cell Differentiation Retinal Rod Cell Differentiation Negative Regulation Of Superoxide Anion Generation Release From Viral Latency Regulation Of Gliogenesis Renal Vesicle Induction
Tagcloud ?			1beta attraction ccl2 ccl7 cd40 chemokines csf1 cxcl10 dark dendrites elongation enforced exert homer1a ht22 microglia mononuclear movement nrem phagocytes profoundly sleep somnogeneic stimulate synapses tnf vicinity wake wakefulness
Tagcloud (Difference) ?			1beta attraction ccl2 ccl7 cd40 chemokines csf1 cxcl10 dark dendrites elongation enforced exert homer1a ht22 microglia mononuclear movement nrem phagocytes profoundly sleep somnogeneic stimulate synapses tnf vicinity wake wakefulness
Tagcloud (Intersection) ?