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NKIRAS2 and NFKBIB
Number of citations of the paper that reports this interaction (PubMedID
10657303
)
0
Data Source:
HPRD
(in vitro, in vivo)
NKIRAS2
NFKBIB
Description
NFKB inhibitor interacting Ras like 2
NFKB inhibitor beta
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Nucleus
Cytoplasm
Cytosol
Molecular Function
Nucleotide Binding
GTPase Activity
Protein Binding
GTP Binding
GTPase Activating Protein Binding
Transcription Coactivator Activity
Protein Binding
Biological Process
Inflammatory Response
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Ral Protein Signal Transduction
Regulation Of Canonical NF-kappaB Signal Transduction
Negative Regulation Of Canonical NF-kappaB Signal Transduction
Surfactant Homeostasis
Lung Alveolus Development
DNA-templated Transcription
Inflammatory Response
Signal Transduction
Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of DNA-templated Transcription
Cellular Response To Lipopolysaccharide
Pathways
RIP-mediated NFkB activation via ZBP1
TAK1-dependent IKK and NF-kappa-B activation
TRAF6 mediated NF-kB activation
Activation of NF-kappaB in B cells
RIP-mediated NFkB activation via ZBP1
TAK1-dependent IKK and NF-kappa-B activation
TRAF6 mediated NF-kB activation
Drugs
Diseases
GWAS
Liver enzyme levels (gamma-glutamyl transferase) (
33972514
)
Interacting Genes
5 interacting genes:
NFKBIA
NFKBIB
PAX6
SMN1
TK1
43 interacting genes:
APP
BAK1
BTBD6
BTRC
CDC25A
CHUK
CSNK2A1
CUL1
DNAJA3
ESR2
FHL3
GIT2
IKBKB
IKBKG
KPNA2
LRPPRC
MCC
MTIF2
NCOR2
NDUFB7
NFKB1
NFKB2
NFKBIA
NGFR
NKIRAS1
NKIRAS2
PDCD2
POLR1A
POLR1B
POLR1C
POLR1D
POLR1E
POLR1G
POLR2H
POLR2L
PPARG
RASAL2
REL
RELA
RXRA
SKP1
TSPAN1
VPS52
Entrez ID
28511
4793
HPRD ID
07261
07260
Ensembl ID
ENSG00000168256
ENSG00000104825
Uniprot IDs
Q9NYR9
G5E9C2
Q15653
PDB IDs
9CK0
Enriched GO Terms of Interacting Partners
?
Nucleobase-containing Compound Biosynthetic Process
Signal Transduction Involved In Regulation Of Gene Expression
Macromolecule Biosynthetic Process
Forebrain-midbrain Boundary Formation
Pancreatic A Cell Development
I-kappaB/NF-kappaB Complex
Nucleic Acid Metabolic Process
Habenula Development
Pallium Development
DNA Synthesis Involved In Mitotic DNA Replication
Thymidine Kinase Activity
Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway
Forebrain Dorsal/ventral Pattern Formation
Regulation Of Asymmetric Cell Division
Oligodendrocyte Cell Fate Specification
Formation Of Anatomical Boundary
Glial Cell Fate Specification
Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain
Cerebral Cortex Regionalization
Lacrimal Gland Development
Telencephalon Regionalization
Thymidine Metabolic Process
Thymidine Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Forebrain Neuron Fate Commitment
Ventral Spinal Cord Development
Iris Morphogenesis
Response To Molecule Of Bacterial Origin
Response To Lipopolysaccharide
Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway
Ubiquitin Protein Ligase Binding
Regulation Of Canonical NF-kappaB Signal Transduction
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Cytosol
Type B Pancreatic Cell Differentiation
HMG Box Domain Binding
Co-SMAD Binding
Regulation Of Timing Of Cell Differentiation
Cornea Development In Camera-type Eye
Salivary Gland Morphogenesis
Negative Regulation Of Neuroblast Proliferation
SMN Complex
Gemini Of Cajal Bodies
Pyrimidine Nucleoside Metabolic Process
Deoxyribonucleoside Monophosphate Biosynthetic Process
Cellular Response To Cold
Dorsal/ventral Axis Specification
Regulation Of Development, Heterochronic
Embryonic Camera-type Eye Morphogenesis
Enteroendocrine Cell Differentiation
RNA Polymerase I Complex
Non-canonical NF-kappaB Signal Transduction
DNA-directed RNA Polymerase Complex
Canonical NF-kappaB Signal Transduction
Nucleoplasm
DNA-directed RNA Polymerase Activity
Intracellular Signal Transduction
Regulation Of Canonical NF-kappaB Signal Transduction
Transcription By RNA Polymerase I
DNA-templated Transcription
Intracellular Signaling Cassette
Negative Regulation Of Canonical NF-kappaB Signal Transduction
I-kappaB/NF-kappaB Complex
Cytosol
Regulation Of Intracellular Signal Transduction
RNA Polymerase III Complex
Regulation Of MiRNA Metabolic Process
Negative Regulation Of Signal Transduction
Nucleobase-containing Compound Biosynthetic Process
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
RRNA Transcription
Tumor Necrosis Factor-mediated Signaling Pathway
IkappaB Kinase Complex
Negative Regulation Of MiRNA Transcription
Regulation Of Signal Transduction
Nucleus
DNA Binding
Macromolecule Biosynthetic Process
Regulation Of MiRNA Transcription
Transferrin Receptor Binding
Signal Transduction Involved In Regulation Of Gene Expression
Immune Response-activating Cell Surface Receptor Signaling Pathway
RNA Metabolic Process
Cellular Response To Tumor Necrosis Factor
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of DNA-binding Transcription Factor Activity
Immune Response-regulating Cell Surface Receptor Signaling Pathway
NF-kappaB P50/p65 Complex
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Response To Cytokine
Response To Peptide
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Response To Tumor Necrosis Factor
Positive Regulation Of T Cell Receptor Signaling Pathway
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