ACTMAP and ANKS1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ACTMAP	ANKS1A
Description		actin maturation protease	ankyrin repeat and sterile alpha motif domain containing 1A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleoplasm Cytoplasm Cytosol Cell Projection Neuron Projection
	Molecular Function	Aminopeptidase Activity Initiator Methionyl Aminopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity Cysteine-type Aminopeptidase Activity	Protein Binding Ephrin Receptor Binding
	Biological Process	Proteolysis Protein Processing	Substrate-dependent Cell Migration Neuron Remodeling Ephrin Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 21378990) Height ( 23563607 28552196 18391951) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Mean platelet volume ( 32888494) Non-small cell lung cancer ( 23144319) Obesity-related traits ( 23251661) Platelet distribution width ( 32888494) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for body mass index ( 25673412 34021172) Waist-hip index ( 34021172)
Interacting Genes		67 interacting genes: A1CF ABI2 AGXT ANKS1A ARID5A COL8A1 CYSRT1 DTX2 ENKD1 FAM222B FANCL FBLIM1 FNDC3B FOXH1 FRS3 GLIS2 GLYCTK GPS2 HOXC8 HR HSF4 IGFN1 INCA1 KCTD9 KPRP KRTAP23-1 KRTAP26-1 LASP1 LMO3 MISP NEDD9 NOXA1 PATZ1 PITX1 PLAC8 PLSCR3 POGZ PRKAB2 PROP1 PRR35 QRICH1 RBPMS RBPMS2 ROR2 SAXO1 SMARCD1 SNRPC SPAG8 TBX6 TCAP TCF7L2 TEKT5 TFG TLE5 TLX3 TOLLIP TRAF4 TRIP13 TROAP VAC14 VENTX WDR25 WWOX YPEL3 ZC2HC1C ZC3H10 ZMYND19	99 interacting genes: ABI2 ACTMAP ADGRL1 ALDOC ANKRD55 ARAP3 ARHGAP10 BCAR1 BLZF1 C17orf50 C22orf39 C3orf36 C9orf152 CADPS CCDC184 CCDC33 CHCHD3 CREBBP CYSRT1 DOK3 EGFR ERBB2 ERBB4 ESM1 FAM217B FAM221A FAM86C1P FCHSD2 FHL5 GOLGA2 GPRIN2 HOXA1 HOXC8 ID3 IKZF3 ISCA2 ITIH6 KCTD9 KEAP1 KIAA1328 KLF15 KLHL26 KPRP KRT31 KRT34 KRT39 KRT75 KRT83 KRTAP10-11 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP19-7 KRTAP4-2 KRTAP6-2 KRTAP9-3 LASP1 LHX2 LNX1 MBD3L1 MED20 MEOX2 MID2 MTUS2 NADSYN1 NBPF19 NEDD9 NHLRC2 NOTCH2NLA NUTM2F PIK3R3 PRDM6 PRKAR1B RANBP3 RB1 RIN1 RNF144B RORB RUSC1 SCN5A SH3KBP1 SHISA6 SLC15A2 SMARCD1 SORBS3 SPATA12 SPRED1 TOX2 TP53BP1 TRIM29 TRIT1 UBC USP54 USP7 YWHAG ZBTB32 ZBTB42 ZC2HC1C ZNF135
Entrez ID		284325	23294
HPRD ID		13449	10610
Ensembl ID		ENSG00000188493	ENSG00000064999
Uniprot IDs		Q5BKX5	Q05CP0 Q92625
PDB IDs			2LMR 2MYQ 6F7O
Enriched GO Terms of Interacting Partners?		Protein Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Myoblast Fate Commitment Transcription Corepressor Activity Positive Regulation Of RNA Metabolic Process Chromatin	Intermediate Filament Keratin Filament Protein Binding Structural Constituent Of Skin Epidermis Intermediate Filament Organization Epidermal Growth Factor Receptor Activity Epidermis Development Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process
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