ACTMAP and WDR25

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ACTMAP	WDR25
Description		actin maturation protease	WD repeat domain 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Aminopeptidase Activity Initiator Methionyl Aminopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity Cysteine-type Aminopeptidase Activity	Protein Binding
	Biological Process	Proteolysis Protein Processing
Pathways
Drugs
Diseases
GWAS			Menarche (age at onset) ( 25231870 27182965) Refractive error ( 32231278) Walking pace ( 33128006)
Interacting Genes		67 interacting genes: A1CF ABI2 AGXT ANKS1A ARID5A COL8A1 CYSRT1 DTX2 ENKD1 FAM222B FANCL FBLIM1 FNDC3B FOXH1 FRS3 GLIS2 GLYCTK GPS2 HOXC8 HR HSF4 IGFN1 INCA1 KCTD9 KPRP KRTAP23-1 KRTAP26-1 LASP1 LMO3 MISP NEDD9 NOXA1 PATZ1 PITX1 PLAC8 PLSCR3 POGZ PRKAB2 PROP1 PRR35 QRICH1 RBPMS RBPMS2 ROR2 SAXO1 SMARCD1 SNRPC SPAG8 TBX6 TCAP TCF7L2 TEKT5 TFG TLE5 TLX3 TOLLIP TRAF4 TRIP13 TROAP VAC14 VENTX WDR25 WWOX YPEL3 ZC2HC1C ZC3H10 ZMYND19	31 interacting genes: ACTMAP AKAP8L CNFN CYSRT1 DVL3 FAM168B FHL3 FOXI1 GOLGA6L9 HSF2BP KRT31 KRT34 KRT40 KRTAP12-3 KRTAP15-1 KRTAP3-1 KRTAP6-3 LDOC1 LNX1 MKRN3 NBPF19 NOTCH2NLA NOTCH3 PFDN5 PNMA1 PRDM14 PSME3 TEPSIN TRIM23 UBXN11 ZNF34
Entrez ID		284325	79446
HPRD ID		13449	14649
Ensembl ID		ENSG00000188493	ENSG00000176473
Uniprot IDs		Q5BKX5	A0A384NPW5 Q64LD2
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Myoblast Fate Commitment Transcription Corepressor Activity Positive Regulation Of RNA Metabolic Process Chromatin	Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Structural Molecule Activity Intermediate Filament Organization
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