ACTMAP and FBLIM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ACTMAP	FBLIM1
Description		actin maturation protease	filamin binding LIM protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Fibrillar Center Stress Fiber Cytoplasm Cytosol Cytoskeleton Focal Adhesion Cell Junction Anchoring Junction Cell Periphery
	Molecular Function	Aminopeptidase Activity Initiator Methionyl Aminopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity Cysteine-type Aminopeptidase Activity	Protein Binding Filamin Binding Metal Ion Binding
	Biological Process	Proteolysis Protein Processing	Cell Adhesion Regulation Of Cell Shape Regulation Of Integrin Activation Cell-cell Adhesion
Pathways			Cell-extracellular matrix interactions
Drugs
Diseases
GWAS			Alcoholic chronic pancreatitis ( 28754779) Cardiac Troponin-T levels ( 23247143) Gut microbiota (bacterial taxa) ( 27723756) Heel bone mineral density ( 30598549)
Interacting Genes		67 interacting genes: A1CF ABI2 AGXT ANKS1A ARID5A COL8A1 CYSRT1 DTX2 ENKD1 FAM222B FANCL FBLIM1 FNDC3B FOXH1 FRS3 GLIS2 GLYCTK GPS2 HOXC8 HR HSF4 IGFN1 INCA1 KCTD9 KPRP KRTAP23-1 KRTAP26-1 LASP1 LMO3 MISP NEDD9 NOXA1 PATZ1 PITX1 PLAC8 PLSCR3 POGZ PRKAB2 PROP1 PRR35 QRICH1 RBPMS RBPMS2 ROR2 SAXO1 SMARCD1 SNRPC SPAG8 TBX6 TCAP TCF7L2 TEKT5 TFG TLE5 TLX3 TOLLIP TRAF4 TRIP13 TROAP VAC14 VENTX WDR25 WWOX YPEL3 ZC2HC1C ZC3H10 ZMYND19	10 interacting genes: ACTMAP ADAT3 FERMT2 FLNA FLNB H3-5 H3C1 LMO3 SHISA6 TRIM15
Entrez ID		284325	54751
HPRD ID		13449	09669
Ensembl ID		ENSG00000188493	ENSG00000162458
Uniprot IDs		Q5BKX5	Q8WUP2
PDB IDs			2K9U 2W0P 4P3W
Enriched GO Terms of Interacting Partners?		Protein Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Myoblast Fate Commitment Transcription Corepressor Activity Positive Regulation Of RNA Metabolic Process Chromatin	Anchoring Junction Focal Adhesion Cell Cortex Actin Filament Binding Positive Regulation Of Substrate Adhesion-dependent Cell Spreading SMAD Binding Regulation Of Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Actin Filament Bundle Assembly Cadherin Binding Protein Localization To Cell Junction Fc-gamma Receptor I Complex Binding Actin Binding Positive Regulation Of Protein Localization To Nucleus Tubulin Deacetylation Myb Complex Stress Fiber Structural Constituent Of Chromatin Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Negative Regulation Of Intracellular Transport Of Viral Material Mesodermal Cell Fate Determination Initiator Methionyl Aminopeptidase Activity Cysteine-type Aminopeptidase Activity Formation Of Radial Glial Scaffolds Establishment Of Sertoli Cell Barrier Nucleosome Asymmetric, Glutamatergic, Excitatory Synapse Regulation Of AMPA Glutamate Receptor Clustering
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