C1QTNF2 and P4HA3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C1QTNF2	P4HA3
Description		C1q and TNF related 2	prolyl 4-hydroxylase subunit alpha 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Binding	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen L-ascorbic Acid Binding Metal Ion Binding Dioxygenase Activity
	Biological Process	Regulation Of Lipid Metabolic Process	Collagen Fibril Organization
Pathways			Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		Weight loss (gastric bypass surgery) ( 23643386)	Hippocampal atrophy ( 25625606)
Interacting Genes		24 interacting genes: AIRIM ANKRD11 BANP CHIC2 GPANK1 HPCA HPCAL1 KCNIP3 KLHL12 LCK LGALS14 MTX2 NCALD NCS1 NOL4 P4HA3 PHOSPHO2 TCEANC TIMM8A TRIM54 UBQLN1 UBQLN2 USP20 VSNL1	49 interacting genes: ACOT8 ADRA2C ANAPC11 ATN1 B9D2 BAG4 BLOC1S2 C1QTNF2 CERCAM CKMT2 CLPP CT55 CTAG1A CTAG1B CTNNBIP1 DTNBP1 FAM136A FIRRM GGA3 GPSM3 HGS KRTAP19-5 KRTAP6-1 KRTAP8-1 LRP2BP MAGEA2 MAGEA2B MAGEC2 MCCD1 MEOX2 MSRA NDN NICN1 NUTM1 OIP5 P4HB PROP1 PSMB4 RBFOX1 RUSC1 SCARA5 SERTAD1 SERTAD3 STMN3 TLE5 TOX2 VPS37C WDR62 ZC3H12A
Entrez ID		114898	283208
HPRD ID		12715	16413
Ensembl ID		ENSG00000145861	ENSG00000149380
Uniprot IDs		A0A499FIM1 Q9BXJ5	Q7Z4N8
PDB IDs
Enriched GO Terms of Interacting Partners?			Protein Binding Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Acetylation Gamma-tubulin Binding
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