GPLD1 and ALPP

Number of citations of the paper that reports this interaction (PMID 11938765)
0

Data Source:
HPRD (in vitro)

		GPLD1	ALPP
Gene Name		glycosylphosphatidylinositol specific phospholipase D1	alkaline phosphatase, placental
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Extracellular Space Intracellular Cytoplasm Lysosomal Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Plasma Membrane Cell Surface Integral Component Of Membrane Anchored Component Of Membrane
	Molecular Function	Glycosylphosphatidylinositol Phospholipase D Activity Phospholipase D Activity Sodium Channel Regulator Activity	Magnesium Ion Binding Alkaline Phosphatase Activity Zinc Ion Binding
	Biological Process	Ossification Cell Migration Involved In Sprouting Angiogenesis Chondrocyte Differentiation Complement Receptor Mediated Signaling Pathway GPI Anchor Release Negative Regulation Of Cell Proliferation Insulin Receptor Signaling Pathway Response To Glucose Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Alkaline Phosphatase Activity Positive Regulation Of Triglyceride Biosynthetic Process Negative Regulation Of Triglyceride Catabolic Process Positive Regulation Of Glucose Metabolic Process Positive Regulation Of High-density Lipoprotein Particle Clearance Cellular Response To Insulin Stimulus Cellular Response To Drug Hematopoietic Stem Cell Migration Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Cytolysis Phosphatidylcholine Metabolic Process Positive Regulation Of Membrane Protein Ectodomain Proteolysis Positive Regulation Of Secretion Transepithelial Transport Cellular Response To Calcium Ion Cellular Response To Cholesterol Cellular Response To Triglyceride Cellular Response To PH Hematopoietic Stem Cell Migration To Bone Marrow Regulation Of Cellular Response To Insulin Stimulus	Dephosphorylation
Pathways
Drugs
Diseases
GWAS		Hematological and biochemical traits ( 20139978) Liver enzyme levels ( 18940312) Liver enzyme levels (alkaline phosphatase) ( 22001757)	Height ( 19570815)
Protein-Protein Interactions		5 interactors: ALPP APOA1 APOA4 CD55 GM2A	7 interactors: ALPPL2 GPLD1 KRTAP10-3 KRTAP4-12 KRTAP5-9 LATS1 PIGK
Entrez ID		2822	250
HPRD ID		03946	01379
Ensembl ID		ENSG00000112293	ENSG00000163283
Uniprot IDs		P80108	P05187
PDB IDs			1EW2 1ZEB 1ZED 1ZEF 2GLQ 3MK0 3MK1 3MK2
Enriched GO Terms of Interacting Partners?		High-density Lipoprotein Particle Assembly Positive Regulation Of Triglyceride Catabolic Process Positive Regulation Of Cholesterol Esterification Regulation Of Intestinal Cholesterol Absorption Regulation Of Cholesterol Esterification Phospholipid Efflux Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Lipoprotein Lipase Activity High-density Lipoprotein Particle Remodeling Protein-lipid Complex Assembly Reverse Cholesterol Transport Positive Regulation Of Lipid Catabolic Process Plasma Lipoprotein Particle Remodeling Positive Regulation Of Steroid Metabolic Process Cholesterol Efflux Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Cholesterol Biosynthetic Process Lipid Transport Regulation Of Triglyceride Metabolic Process Triglyceride Homeostasis Acylglycerol Homeostasis Regulation Of Cholesterol Transport Lipid Localization Lipid Storage Sterol Biosynthetic Process Neuron Projection Regeneration Phosphatidylcholine Metabolic Process Regulation Of Lipid Catabolic Process Positive Regulation Of Lipid Biosynthetic Process Regulation Of Plasma Lipoprotein Particle Levels Sterol Transport Cholesterol Transport Phototransduction, Visible Light Cholesterol Homeostasis Retinoid Metabolic Process Sterol Homeostasis Regulation Of Fatty Acid Metabolic Process Diterpenoid Metabolic Process Positive Regulation Of Lipase Activity Detection Of Visible Light Phospholipid Transport Regulation Of Lipid Transport Phototransduction Regulation Of Steroid Metabolic Process Detection Of Light Stimulus Negative Regulation Of Cell Adhesion Molecule Production Cholesterol Metabolic Process Lipid Homeostasis Steroid Biosynthetic Process	GPI Anchor Metabolic Process GPI Anchor Release Cellular Response To Triglyceride Glycolipid Metabolic Process Positive Regulation Of High-density Lipoprotein Particle Clearance Hematopoietic Stem Cell Migration To Bone Marrow Hematopoietic Stem Cell Migration Positive Regulation Of Cytolysis Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Negative Regulation Of Triglyceride Catabolic Process Complement Receptor Mediated Signaling Pathway Phosphate-containing Compound Metabolic Process Epidermis Development Response To Triglyceride Glycerophospholipid Metabolic Process Attachment Of GPI Anchor To Protein Glycerolipid Metabolic Process Phospholipid Metabolic Process Positive Regulation Of Membrane Protein Ectodomain Proteolysis Transepithelial Transport Cellular Response To PH Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Alkaline Phosphatase Activity Cellular Response To Cholesterol Tissue Development Cellular Response To Sterol Regulation Of Triglyceride Biosynthetic Process Cell Migration Involved In Sprouting Angiogenesis Response To Cholesterol Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Negative Regulation Of Lipid Catabolic Process Cytoplasmic Sequestering Of Protein Hippo Signaling Cellular Response To Hormone Stimulus C-terminal Protein Lipidation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Protein Transport Positive Regulation Of Phosphatase Activity Blood Vessel Endothelial Cell Migration Positive Regulation Of Glucose Metabolic Process Regulation Of Triglyceride Metabolic Process Regulation Of Establishment Of Protein Localization Response To PH
Tagcloud ?			adsc adscs buffered capacities coinjection encapsulated ganglia glycolic intramuscularly lactic leak masson microspheres nerves ngf pbs periurethral plga pnt pudendal reassessed retrograde rupp sui transection trichrome trk urethra urodynamic
Tagcloud (Difference) ?			adsc adscs buffered capacities coinjection encapsulated ganglia glycolic intramuscularly lactic leak masson microspheres nerves ngf pbs periurethral plga pnt pudendal reassessed retrograde rupp sui transection trichrome trk urethra urodynamic
Tagcloud (Intersection) ?