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GPLD1
Gene Name
glycosylphosphatidylinositol specific phospholipase D1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Proteinaceous Extracellular Matrix
Extracellular Space
Intracellular
Cytoplasm
Lysosomal Membrane
Intracellular Membrane-bounded Organelle
Extracellular Vesicular Exosome
Molecular Function
Glycosylphosphatidylinositol Phospholipase D Activity
Phospholipase D Activity
Sodium Channel Regulator Activity
Biological Process
Ossification
Cell Migration Involved In Sprouting Angiogenesis
Chondrocyte Differentiation
Complement Receptor Mediated Signaling Pathway
GPI Anchor Release
Negative Regulation Of Cell Proliferation
Insulin Receptor Signaling Pathway
Response To Glucose
Positive Regulation Of Endothelial Cell Migration
Positive Regulation Of Alkaline Phosphatase Activity
Positive Regulation Of Triglyceride Biosynthetic Process
Negative Regulation Of Triglyceride Catabolic Process
Positive Regulation Of Glucose Metabolic Process
Positive Regulation Of High-density Lipoprotein Particle Clearance
Cellular Response To Insulin Stimulus
Cellular Response To Drug
Hematopoietic Stem Cell Migration
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Positive Regulation Of Apoptotic Process
Positive Regulation Of Cytolysis
Phosphatidylcholine Metabolic Process
Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Positive Regulation Of Secretion
Transepithelial Transport
Cellular Response To Calcium Ion
Cellular Response To Cholesterol
Cellular Response To Triglyceride
Cellular Response To PH
Hematopoietic Stem Cell Migration To Bone Marrow
Regulation Of Cellular Response To Insulin Stimulus
Pathways
Drugs
Diseases
GWAS
Hematological and biochemical traits (
20139978
)
Liver enzyme levels (
18940312
)
Liver enzyme levels (alkaline phosphatase) (
22001757
)
Protein-protein Interactions
5 interactors:
ALPP
APOA1
APOA4
CD55
GM2A
Entrez ID
2822
HPRD ID
03946
Ensembl ID
ENSG00000112293
Uniprot IDs
P80108
PDB IDs
Enriched GO Terms of Interacting Partners
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High-density Lipoprotein Particle Assembly
Positive Regulation Of Triglyceride Catabolic Process
Positive Regulation Of Cholesterol Esterification
Regulation Of Intestinal Cholesterol Absorption
Regulation Of Cholesterol Esterification
Phospholipid Efflux
Positive Regulation Of Fatty Acid Biosynthetic Process
Positive Regulation Of Lipoprotein Lipase Activity
High-density Lipoprotein Particle Remodeling
Protein-lipid Complex Assembly
Reverse Cholesterol Transport
Positive Regulation Of Lipid Catabolic Process
Plasma Lipoprotein Particle Remodeling
Positive Regulation Of Steroid Metabolic Process
Cholesterol Efflux
Positive Regulation Of Fatty Acid Metabolic Process
Regulation Of Fatty Acid Biosynthetic Process
Cholesterol Biosynthetic Process
Lipid Transport
Regulation Of Triglyceride Metabolic Process
Triglyceride Homeostasis
Acylglycerol Homeostasis
Regulation Of Cholesterol Transport
Lipid Localization
Lipid Storage
Sterol Biosynthetic Process
Neuron Projection Regeneration
Phosphatidylcholine Metabolic Process
Regulation Of Lipid Catabolic Process
Positive Regulation Of Lipid Biosynthetic Process
Regulation Of Plasma Lipoprotein Particle Levels
Sterol Transport
Cholesterol Transport
Phototransduction, Visible Light
Cholesterol Homeostasis
Retinoid Metabolic Process
Sterol Homeostasis
Regulation Of Fatty Acid Metabolic Process
Diterpenoid Metabolic Process
Positive Regulation Of Lipase Activity
Detection Of Visible Light
Phospholipid Transport
Regulation Of Lipid Transport
Phototransduction
Regulation Of Steroid Metabolic Process
Detection Of Light Stimulus
Negative Regulation Of Cell Adhesion Molecule Production
Cholesterol Metabolic Process
Lipid Homeostasis
Steroid Biosynthetic Process
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