GP1BB and TGFB1I1

Number of citations of the paper that reports this interaction (PMID 20946164)
8

Data Source:
BioGRID (pull down, affinity chromatography technology)

		GP1BB	TGFB1I1
Gene Name		glycoprotein Ib (platelet), beta polypeptide	transforming growth factor beta 1 induced transcript 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Intracellular Cytoplasm Cytoskeleton Focal Adhesion Nuclear Matrix Extracellular Matrix
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Roundabout Binding Androgen Receptor Binding I-SMAD Binding
	Biological Process	Cell Adhesion Cell Surface Receptor Signaling Pathway Blood Coagulation Blood Coagulation, Intrinsic Pathway Platelet Activation	Transcription From RNA Polymerase II Promoter Cell Adhesion Negative Regulation Of Cell Proliferation Response To Heat Positive Regulation Of Epithelial To Mesenchymal Transition Wnt Signaling Pathway Morphogenesis Of Embryonic Epithelium Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Androgen Receptor Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Epithelial Cell Differentiation Cell Fate Commitment Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways		Platelet Adhesion to exposed collagen Intrinsic Pathway GP1b-IX-V activation signalling Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation) Formation of Fibrin Clot (Clotting Cascade)
Drugs
Diseases
GWAS		DNA methylation (parent-of-origin) ( 23725790)
Protein-Protein Interactions		4 interactors: GP9 PRKACA TGFB1I1 YWHAZ	29 interactors: AR CBLB CBLC CDKN2B CRKL CSK EP300 FKBP1A GIT1 GIT2 GP1BB HIPK3 HSPB1 ITGA4 MAPK15 NEDD4L NR3C1 PLA2G3 PTK2 PTK2B PTPN12 SDC4 SLC6A3 SMAD7 SVIL TGFBR2 TRAF4 UBQLN4 VCL
Entrez ID		2812	7041
HPRD ID		00729	03831
Ensembl ID			ENSG00000140682
Uniprot IDs		P13224	O43294
PDB IDs		3REZ 3RFE
Enriched GO Terms of Interacting Partners?		Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Positive Regulation Of Dense Core Granule Biogenesis Morphogenesis Of Embryonic Epithelium Histone H3-T6 Phosphorylation Intrinsic Apoptotic Signaling Pathway Response To Stress Cell Adhesion Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Transport Golgi Reassembly Histamine Secretion By Mast Cell Ubiquitin-dependent SMAD Protein Catabolic Process Peptidyl-serine Autophosphorylation Establishment Of Golgi Localization Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Golgi Inheritance Apoptotic Signaling Pathway Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Histamine Secretion Regulation Of Tight Junction Assembly Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Histamine Transport Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Intracellular Transport Endomembrane System Organization Regulation Of Cellular Component Organization Calcium-mediated Signaling Using Intracellular Calcium Source Desmosome Organization Response To Parathyroid Hormone Positive Regulation Of Protein Export From Nucleus Cell Communication By Electrical Coupling Golgi Localization Activation Of Protein Kinase A Activity Blood Coagulation, Intrinsic Pathway Morphogenesis Of An Epithelium Negative Regulation Of Glucose Transport Cellular Response To Epinephrine Stimulus Regulation Of Platelet Aggregation Sperm Capacitation Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion	Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Regulation Of Protein Phosphorylation Regulation Of Signal Transduction Regulation Of Phosphorus Metabolic Process Regulation Of Signaling Regulation Of Cellular Protein Metabolic Process Cell Activation Positive Regulation Of Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Regulation Of Kinase Activity Enzyme Linked Receptor Protein Signaling Pathway Signaling Cell Communication Signal Transduction Response To Stimulus Regulation Of Catalytic Activity Transforming Growth Factor Beta Receptor Signaling Pathway Response To Organic Substance Organ Development Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Modification Process Cellular Response To Organic Substance Cellular Response To Transforming Growth Factor Beta Stimulus Cell Surface Receptor Signaling Pathway System Development Response To Transforming Growth Factor Beta Regulation Of Metabolic Process Positive Regulation Of Protein Catabolic Process Anatomical Structure Development Regulation Of Protein Catabolic Process Negative Regulation Of Signal Transduction Cellular Response To Growth Factor Stimulus Negative Regulation Of Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Ubiquitination Response To Growth Factor Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Phosphorylation Response To Organic Cyclic Compound Negative Regulation Of Signaling Cellular Response To Stimulus Multicellular Organismal Development Regulation Of Cellular Process Positive Regulation Of Protein Kinase Activity Developmental Process Positive Regulation Of Kinase Activity Negative Regulation Of Transferase Activity Positive Regulation Of Protein Phosphorylation
Tagcloud ?			aii aiii aiiis aiis astrocytoma astrocytomas beta1 bioinformatics biomarker contributing emt focused grade grades idh1 integration malignant microarrays multistep nbt progress progression qpcr shrna tp53 transcript transition validated
Tagcloud (Difference) ?			aii aiii aiiis aiis astrocytoma astrocytomas beta1 bioinformatics biomarker contributing emt focused grade grades idh1 integration malignant microarrays multistep nbt progress progression qpcr shrna tp53 transcript transition validated
Tagcloud (Intersection) ?