GP1BB

Gene Name		glycoprotein Ib (platelet), beta polypeptide
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding
	Biological Process	Cell Adhesion Cell Surface Receptor Signaling Pathway Blood Coagulation Blood Coagulation, Intrinsic Pathway Platelet Activation
Pathways		Platelet Adhesion to exposed collagen Intrinsic Pathway GP1b-IX-V activation signalling Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation) Formation of Fibrin Clot (Clotting Cascade)
Drugs
Diseases
GWAS		DNA methylation (parent-of-origin) ( 23725790)
Protein-protein Interactions		4 interactors: GP9 PRKACA TGFB1I1 YWHAZ
Entrez ID		2812
HPRD ID		00729
Ensembl ID
Uniprot IDs		P13224
PDB IDs		3REZ 3RFE
Enriched GO Terms of Interacting Partners?		Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Positive Regulation Of Dense Core Granule Biogenesis Morphogenesis Of Embryonic Epithelium Histone H3-T6 Phosphorylation Intrinsic Apoptotic Signaling Pathway Response To Stress Cell Adhesion Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Transport Golgi Reassembly Histamine Secretion By Mast Cell Ubiquitin-dependent SMAD Protein Catabolic Process Peptidyl-serine Autophosphorylation Establishment Of Golgi Localization Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Golgi Inheritance Apoptotic Signaling Pathway Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Histamine Secretion Regulation Of Tight Junction Assembly Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Histamine Transport Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Intracellular Transport Endomembrane System Organization Regulation Of Cellular Component Organization Calcium-mediated Signaling Using Intracellular Calcium Source Desmosome Organization Response To Parathyroid Hormone Positive Regulation Of Protein Export From Nucleus Cell Communication By Electrical Coupling Golgi Localization Activation Of Protein Kinase A Activity Blood Coagulation, Intrinsic Pathway Morphogenesis Of An Epithelium Negative Regulation Of Glucose Transport Cellular Response To Epinephrine Stimulus Regulation Of Platelet Aggregation Sperm Capacitation Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
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