GOLGA1 and EXOC4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GOLGA1	EXOC4
Description		golgin A1	exocyst complex component 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Vesicle Golgi Apparatus Trans-Golgi Network Cytosol Membrane Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm	Exocyst Cytoplasm Centrosome Cytosol Cytoskeleton Plasma Membrane Microvillus Membrane Growth Cone Membrane Myelin Sheath Abaxonal Region Cell Projection Neuron Projection Synapse Flemming Body
	Molecular Function	Protein Binding Molecular Carrier Activity	Protein Binding PDZ Domain Binding
	Biological Process	Cell-cell Adhesion Mediated By Cadherin Transepithelial Transport	Mitotic Cytokinesis Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Chemical Synaptic Transmission Protein Transport Regulation Of Macroautophagy Paraxial Mesoderm Formation Protein Transmembrane Transport Membrane Fission Vesicle Tethering Involved In Exocytosis
Pathways		Retrograde transport at the Trans-Golgi-Network	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS			Age at first sexual intercourse ( 34211149) Alzheimer's disease (cognitive decline) ( 23535033) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Food allergy ( 29030101) Fruit consumption ( 32066663) General cognitive ability ( 29844566) Household income (MTAG) ( 31844048) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Moderate to vigorous physical activity levels ( 29899525) Mood instability ( 31168069) Peanut allergy ( 29030101) Plasma anti-thyroid peroxidase levels ( 29678681) QT interval ( 29213071) Response to selective serotonin reuptake inhibitors in depression ( 30034349) Subcortical volume (MOSTest) ( 32665545) Tonometry ( 17903302) Vigorous physical activity ( 29899525)
Interacting Genes		22 interacting genes: ARL1 ATF4 ATXN10 CEP57L1 EFHC2 EXOC4 HSF2BP KIAA1328 KIFC3 KRT27 LZTS1 PDCL2 PPP1R13B PRKAR1B RAB6A SLAIN1 TFIP11 TP53BP2 UBE2I VPS52 ZC2HC1C ZNF774	16 interacting genes: BIRC6 CCHCR1 CEP63 DISC1 DLG3 DLG4 DLGAP4 EXOC7 GOLGA1 GRIN2B ING1 MBD3 RALA SMARCE1 TTC3 WEE2-AS1
Entrez ID		2800	60412
HPRD ID		03934	12185
Ensembl ID		ENSG00000136935	ENSG00000131558
Uniprot IDs		Q92805	Q6NX51 Q96A65
PDB IDs			7PC5
Enriched GO Terms of Interacting Partners?			Flemming Body Synaptic Membrane Neuromuscular Junction Microtubule Organizing Center Postsynaptic Density Membrane Ionotropic Glutamate Receptor Binding AMPA Glutamate Receptor Complex Ionotropic Glutamate Receptor Signaling Pathway Regulation Of Synapse Maturation Positive Regulation Of Excitatory Postsynaptic Potential Response To Methotrexate Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Receptor Clustering Receptor Localization To Synapse P2Y1 Nucleotide Receptor Binding Glutamate Receptor Signaling Pathway Ligand-gated Ion Channel Signaling Pathway Modulation Of Excitatory Postsynaptic Potential Modulation Of Chemical Synaptic Transmission Positive Regulation Of Stem Cell Population Maintenance Nucleosomal DNA Binding Molecular Adaptor Activity Protein Localization To Synapse Regulation Of Neuronal Synaptic Plasticity
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