TMEM97 and TMEM79

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM97	TMEM79
Description		transmembrane protein 97	transmembrane protein 79
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Lysosome Endoplasmic Reticulum Rough Endoplasmic Reticulum Plasma Membrane Membrane Rough Endoplasmic Reticulum Membrane Nuclear Membrane	Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Oxysterol Binding Cholesterol Binding	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Cell Growth Regulation Of Intracellular Lipid Transport Regulation Of Intracellular Cholesterol Transport Cholesterol Homeostasis Positive Regulation Of Wound Healing Positive Regulation Of Lipoprotein Transport	Epithelial Cell Maturation Hair Follicle Morphogenesis Cuticle Development Regulated Exocytosis Positive Regulation Of Epidermis Development Establishment Of Skin Barrier Cornification
Pathways
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Osteoprotegerin levels ( 25080503)	Glycated hemoglobin levels ( 24647736 28898252 29170429) Mean corpuscular hemoglobin concentration ( 20139978)
Interacting Genes		66 interacting genes: APP AQP12B AQP2 AQP6 ARL13B ASZ1 ATP6AP2 BCL2L13 BIK CD53 CD74 CD79A CGRRF1 CLDN7 CLSTN3 CPLX4 EBP ERGIC3 FAM209A FFAR2 FKBP7 FRMD3 FXYD3 GJA8 GJB3 GJB5 GPR152 GPR37L1 GPX8 HSD17B13 IFNGR2 KIR2DL3 LEUTX LHFPL5 LIME1 LRRC59 MFF MRM1 MTIF3 MUC1 NDUFAF1 NDUFAF2 NEMP1 PDCD1LG2 PDZK1IP1 PLP1 PSCA REEP1 RHCG RNF170 SAR1A SGPL1 SLC10A1 SLC14A1 SLC14A2 SLC18A1 SLC35H1 SPINT1 SSMEM1 TMEM106C TMEM14B TMEM45B TMEM52B TMEM79 TMX2 VSIR	36 interacting genes: ABO AMIGO1 ANKRD46 APOD ARL13B BRICD5 CLEC7A COQ9 CPLX4 CYB5R3 FAM209A FNDC9 GIMAP1 GPRC5D LDLRAD1 LPAR3 PELI2 PLN PLP2 PVR RNF8 RPRM SEC22A SERP1 SFTPC SLN TEX264 TMEM100 TMEM14C TMEM254 TMEM97 TMPRSS2 TMPRSS4 TNMD TRAM1L1 ZCCHC12
Entrez ID		27346	84283
HPRD ID		14343	17481
Ensembl ID		ENSG00000109084	ENSG00000163472
Uniprot IDs		Q5BJF2	Q9BSE2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Water Transport One-carbon Compound Transport Fluid Transport Protein Binding Water Channel Activity Endoplasmic Reticulum Membrane Connexin Complex Endoplasmic Reticulum Gap Junction Channel Activity Plasma Membrane B Cell Receptor Complex Water Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Mitochondrial Membrane Gap Junction Urea Transmembrane Transporter Activity Transmembrane Transport	Membrane Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Endoplasmic Reticulum Endoplasmic Reticulum Membrane Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Negative Regulation Of Intracellular Transport Negative Regulation Of ATP-dependent Activity Negative Regulation Of Calcium Ion Import Positive Regulation Of Viral Entry Into Host Cell Regulation Of Relaxation Of Muscle
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