TMEM97 and NEMP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM97	NEMP1
Description		transmembrane protein 97	nuclear envelope integral membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Lysosome Endoplasmic Reticulum Rough Endoplasmic Reticulum Plasma Membrane Membrane Rough Endoplasmic Reticulum Membrane Nuclear Membrane	Nucleus Nuclear Envelope Nuclear Inner Membrane Membrane
	Molecular Function	Protein Binding Oxysterol Binding Cholesterol Binding	Protein Binding
	Biological Process	Regulation Of Cell Growth Regulation Of Intracellular Lipid Transport Regulation Of Intracellular Cholesterol Transport Cholesterol Homeostasis Positive Regulation Of Wound Healing Positive Regulation Of Lipoprotein Transport	Erythrocyte Enucleation Erythrocyte Maturation Nuclear Membrane Organization
Pathways
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Osteoprotegerin levels ( 25080503)	Asthma ( 31959851)
Interacting Genes		66 interacting genes: APP AQP12B AQP2 AQP6 ARL13B ASZ1 ATP6AP2 BCL2L13 BIK CD53 CD74 CD79A CGRRF1 CLDN7 CLSTN3 CPLX4 EBP ERGIC3 FAM209A FFAR2 FKBP7 FRMD3 FXYD3 GJA8 GJB3 GJB5 GPR152 GPR37L1 GPX8 HSD17B13 IFNGR2 KIR2DL3 LEUTX LHFPL5 LIME1 LRRC59 MFF MRM1 MTIF3 MUC1 NDUFAF1 NDUFAF2 NEMP1 PDCD1LG2 PDZK1IP1 PLP1 PSCA REEP1 RHCG RNF170 SAR1A SGPL1 SLC10A1 SLC14A1 SLC14A2 SLC18A1 SLC35H1 SPINT1 SSMEM1 TMEM106C TMEM14B TMEM45B TMEM52B TMEM79 TMX2 VSIR	31 interacting genes: ADIPOQ AQP10 ASGR1 BRICD5 C3orf52 C5 CD81 CLEC7A CLRN2 CNIH3 COL4A5 CXCL16 CXCL9 FAXDC2 GPR108 GUCA2A INSIG2 PNLIPRP1 RTP2 SCARF1 SERP2 STX12 TMEM14A TMEM229B TMEM42 TMEM86B TMEM97 TMUB2 TSPAN33 UPK1B VAMP3
Entrez ID		27346	23306
HPRD ID		14343	13793
Ensembl ID		ENSG00000109084	ENSG00000166881
Uniprot IDs		Q5BJF2	O14524
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Water Transport One-carbon Compound Transport Fluid Transport Protein Binding Water Channel Activity Endoplasmic Reticulum Membrane Connexin Complex Endoplasmic Reticulum Gap Junction Channel Activity Plasma Membrane B Cell Receptor Complex Water Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Mitochondrial Membrane Gap Junction Urea Transmembrane Transporter Activity Transmembrane Transport	Membrane Protein Localization To Cell Periphery Localization Within Membrane Chemokine Activity Tetraspanin-enriched Microdomain Receptor-mediated Endocytosis Positive Regulation Of Chemokine Production Protein Localization To Membrane Positive Regulation Of Monocyte Chemotactic Protein-1 Production Oxysterol Binding Protein Localization To Plasma Membrane
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