SLC13A5 and KRTAP12-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC13A5	KRTAP12-2
Description		solute carrier family 13 member 5	keratin associated protein 12-2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Membrane	Cytosol Intermediate Filament
	Molecular Function	Organic Acid:sodium Symporter Activity Protein Binding Citrate Transmembrane Transporter Activity Succinate Transmembrane Transporter Activity Tricarboxylic Acid Transmembrane Transporter Activity Symporter Activity Solute:sodium Symporter Activity Sodium:dicarboxylate Symporter Activity Transmembrane Transporter Activity Identical Protein Binding	Protein Binding
	Biological Process	Monoatomic Ion Transport Sodium Ion Transport Tricarboxylic Acid Transport Oxaloacetate Transport Fumarate Transport Alpha-ketoglutarate Transport Succinate Transport Citrate Transport Tricarboxylic Acid Transmembrane Transport Sodium Ion Transmembrane Transport Transmembrane Transport Cellular Response To Lithium Ion Succinate Transmembrane Transport Organic Acid Transmembrane Transport
Pathways		SLC-mediated transport of organic anions	Keratinization
Drugs
Diseases
GWAS		Economic and political preferences (time) ( 22566634) LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		18 interacting genes: ADAMTSL4 CD79A CYSRT1 GJA8 GOLM1 KLHL20 KRTAP1-3 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP3-2 KRTAP5-2 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 MDFI	127 interacting genes: ADAM12 ARID5A ATN1 ATP6V1C2 AVPI1 BCL6B BEX2 CATSPER1 CBLL2 CBX2 CCNL1 CCNL2 CFP CHRD CNNM3 CYSRT1 DGCR6 DHRS1 EFEMP2 ETNK2 FAM27E3 FHL3 FOXD4 FOXD4L1 FOXD4L3 GDF15 GPANK1 GPRIN2 GREM1 HOXA1 HOXB9 HSFX1 HSFX2 HYPK INO80B IQUB KRT34 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP21-2 KRTAP26-1 KRTAP3-2 KRTAP4-2 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1F LCE2A LCE2B LCE4A LCE5A LINC00671 MEOX2 MGAT5B MYOZ1 MYPOP NBPF19 NECTIN2 NOTCH2NLA NPDC1 NR1D2 ODF1 OTX1 PACSIN3 PATZ1 PCSK5 PDE9A PELO PHLDA1 PIH1D2 PLAC8 POLR1C POM121L8P POU4F2 RAD23A RBM39 RBPMS RBX1 RHOXF2 SEMA3B SLC12A4 SLC13A5 SLC15A2 SLC15A3 SPATA3 SPMIP9 SPRED2 SPRY1 SRSF8 TCEA2 TINAGL1 TLE5 TMEM179B TNS2 TRIM42 TRIP13 TSGA10IP TTPA VASN VENTX VGLL3 YIPF3 YY1 ZBTB9 ZDHHC1 ZIM2 ZNF100 ZNF408 ZNF497 ZNF581 ZNF587 ZNF624 ZNF688 ZNF696 ZNF764 ZNF785 ZNHIT1
Entrez ID		284111	353323
HPRD ID		10512	11198
Ensembl ID		ENSG00000141485	ENSG00000221864
Uniprot IDs		Q86YT5	P59991
PDB IDs		7JSJ 7JSK 8UVB 8UVH
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Identical Protein Binding Type II Interferon Binding Pigment Cell Development	Intermediate Filament Keratinization Keratin Filament Epidermis Development Protein Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Sequence-specific DNA Binding Tissue Development Regulation Of Nucleobase-containing Compound Metabolic Process Peptidoglycan Transport Identical Protein Binding Peptide:proton Symporter Activity Dipeptide Transmembrane Transporter Activity Negative Regulation Of Lens Fiber Cell Differentiation Dipeptide Transmembrane Transport Dipeptide Import Across Plasma Membrane Dipeptide Transport
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