VPS4A and PLA2G15

		VPS4A	PLA2G15
Description		vacuolar protein sorting 4 homolog A	phospholipase A2 group XV
Image
GO Annotations	Cellular Component	Spindle Pole Nucleus Nuclear Pore Cytoplasm Lysosome Endosome Early Endosome Late Endosome Vacuolar Membrane Centrosome Spindle Cytosol Cytoskeleton Plasma Membrane Endosome Membrane Membrane Midbody Late Endosome Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Flemming Body ATPase Complex	Extracellular Region Extracellular Space Nucleoplasm Lysosome Membrane Extracellular Exosome
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Protein-containing Complex Binding ATP-dependent Protein Disaggregase Activity	Phosphatidylcholine Lysophospholipase Activity Phospholipase A2 Activity Protein Binding Phospholipid Binding Zinc Ion Binding O-acyltransferase Activity Phospholipase A1 Activity Acylglycerol O-acyltransferase Activity Transferase Activity Acyltransferase Activity Hydrolase Activity Metal Ion Binding Calcium-independent Phospholipase A2 Activity
	Biological Process	Actomyosin Contractile Ring Contraction Plasma Membrane Repair Protein Targeting To Lysosome Vesicle Budding From Membrane Autophagy Nucleus Organization Nuclear Envelope Organization Endosome Organization Vacuole Organization Lysosomal Transport Mitotic Metaphase Chromosome Alignment Mitotic Nuclear Membrane Reassembly Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Vesicle-mediated Transport Endosomal Transport Macroautophagy Viral Release From Host Cell Nuclear Membrane Reassembly Intracellular Cholesterol Transport Negative Regulation Of Cytokinesis Regulation Of Protein Localization Endosomal Vesicle Fusion Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Cytokinesis Checkpoint Signaling Viral Budding From Plasma Membrane Protein Depolymerization Cell Division Cytoskeleton-dependent Cytokinesis Late Endosomal Microautophagy Late Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Midbody Abscission Multivesicular Body Sorting Pathway Vesicle Uncoating Membrane Fission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Autophagosome Maturation Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Exosomal Secretion Positive Regulation Of Viral Budding Via Host ESCRT Complex ESCRT Complex Disassembly ESCRT III Complex Disassembly	Lipid Metabolic Process Fatty Acid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Diacylglycerol Biosynthetic Process Phosphatidylserine Metabolic Process Ceramide Metabolic Process Fatty Acid Catabolic Process Lipid Catabolic Process Phosphatidylcholine Catabolic Process Phosphatidylethanolamine Catabolic Process Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process
Pathways		Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Sealing of the nuclear envelope (NE) by ESCRT-III	Hydrolysis of LPC
Drugs
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) HDL cholesterol ( 30275531) Logical memory (delayed recall) in normal cognition ( 29274321) Total cholesterol levels in HDL ( 29084231)	Body size at age 10 ( 32376654) Eosinophil count ( 27863252) Eosinophil percentage of white cells ( 27863252) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Serum metabolite levels ( 33031748) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		13 interacting genes: CFTR CHMP1A CHMP1B CHMP2A CHMP4A CHMP4B CHMP4C CLIC3 NPC1 OGT RND2 SNCA VPS4B	2 interacting genes: IMMT RNF7
Entrez ID		27183	23659
HPRD ID		11676	07128
Ensembl ID		ENSG00000132612	ENSG00000103066
Uniprot IDs		Q9UN37	B4DJW4 Q8NCC3
PDB IDs		1YXR 2JQ9 2K3W	4X90 4X91 4X92 4X93 4X94 4X95 4X97 6MTW
Enriched GO Terms of Interacting Partners?		Viral Budding From Plasma Membrane Late Endosome To Lysosome Transport Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Midbody Abscission Viral Budding Nuclear Membrane Reassembly Mitotic Cytokinetic Process ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Multivesicular Body-lysosome Fusion Multivesicular Body Assembly Multivesicular Body Organization Regulation Of Spindle Assembly Lysosomal Membrane Organization Late Endosome To Vacuole Transport Cytokinetic Process Endosome Transport Via Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Organization Membrane Fission Mitotic Metaphase Chromosome Alignment Multivesicular Body Sorting Pathway Kinetochore Microtubule Nuclear Membrane Organization Autophagosome Maturation Metaphase Chromosome Alignment Membrane Assembly Lysosomal Transport Multivesicular Body Membrane Chromosome Localization Biological Process Involved In Interaction With Host Endosome Organization Regulation Of Microtubule Cytoskeleton Organization Nuclear Pore Vacuolar Transport Autophagy Nucleus Organization Multivesicular Body Regulation Of Centrosome Duplication Autophagosome Membrane Plasma Membrane Organization Regulation Of Centrosome Cycle Regulation Of Microtubule-based Process Protein-containing Complex Disassembly Viral Process Organelle Localization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?