KCNAB1 and SLC39A2

Number of citations of the paper that reports this interaction (PubMedID 10477520)
0

Data Source:
HPRD (two hybrid)

		KCNAB1	SLC39A2
Description		potassium voltage-gated channel subfamily A regulatory beta subunit 1	solute carrier family 39 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Voltage-gated Potassium Channel Complex Cytoplasmic Side Of Plasma Membrane Membrane Potassium Channel Complex Juxtaparanode Region Of Axon	Plasma Membrane Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Carbonyl Reductase (NADPH) Activity Voltage-gated Potassium Channel Activity Protein Binding Alcohol Dehydrogenase (NADP+) Activity Potassium Channel Regulator Activity Oxidoreductase Activity Protein Domain Specific Binding Transmembrane Transporter Binding NADPH Binding Molecular Function Inhibitor Activity	Zinc Ion Transmembrane Transporter Activity Protein Binding Metal Ion Transmembrane Transporter Activity
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Learning Or Memory Transmembrane Transport Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Voltage-gated Potassium Channel Activity	Monoatomic Ion Transport Zinc Ion Transport Metal Ion Transport Keratinocyte Differentiation Transmembrane Transport Cadmium Ion Transmembrane Transport Zinc Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels	Zinc influx into cells by the SLC39 gene family
Drugs		Enflurane Promethazine Miconazole
Diseases
GWAS		Age-related nuclear cataracts ( 24951543) Aging traits ( 17903295) Bevacizumab-induced hypertension ( 34616010) Coronary artery disease ( 26708285) Focal epilepsy (with hippocampal sclerosis) ( 30531953) Offspring birth weight ( 31043758)
Interacting Genes		9 interacting genes: APP DLG1 FBXO7 KCNA2 NEDD4 NEDD4L SLC39A1 SLC39A2 SRPK1	52 interacting genes: AQP1 AQP6 ARL13B ARLN BCL2L2 BTN2A2 C3orf52 CD79A CLCA4 CNR2 COL4A5 COMT CREB3L1 CXCR2 CYB561 EHHADH EMC6 FAM209A FCER1G FXYD3 FXYD6 GJA8 GPR152 GPR42 KCNAB1 KCNAB2 LY6G6C MFSD6 MS4A13 PLN PNLIPRP1 SEC22A SLC18A1 SLC30A2 SLC30A8 SLC39A1 SLC39A9 SLC66A1 SLC7A1 SSMEM1 ST6GAL2 STATH TMEM107 TMEM14B TMEM229B TMEM237 TMEM54 TMEM60 TMEM86A TRHR UPK1B YIPF6
Entrez ID		7881	29986
HPRD ID		03089	15385
Ensembl ID		ENSG00000169282	ENSG00000165794
Uniprot IDs		B7Z435 B7Z8E5 F8W6W4 Q14722 Q5MJQ3	Q9NP94
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Membrane Potential Regulation Of Monoatomic Cation Transmembrane Transport Synapse Organization Regulation Of Sodium Ion Transport Regulation Of Potassium Ion Transmembrane Transport Metal Ion Transport Sodium Channel Inhibitor Activity Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Potassium Ion Transport Potassium Channel Inhibitor Activity Developmental Process Monoatomic Cation Transport Regulation Of Metal Ion Transport Negative Regulation Of Sodium Ion Transport Regulation Of Monoatomic Ion Transport Transmembrane Transporter Binding Monoatomic Ion Transport Receptor Catabolic Process Metal Ion Transmembrane Transporter Activity Cell Junction Organization Negative Regulation Of Potassium Ion Transmembrane Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Zinc Ion Transport Ionotropic Glutamate Receptor Binding Negative Regulation Of Potassium Ion Transport Positive Regulation Of Catabolic Process Leukocyte Activation Positive Regulation Of Protein Catabolic Process Plasma Membrane Neuromuscular Junction Development Regulation Of Sodium Ion Transmembrane Transport Inorganic Cation Transmembrane Transport Monoatomic Cation Transmembrane Transport Regulation Of Plasma Membrane Bounded Cell Projection Organization Cell Activation Regulation Of Cell Projection Organization Ubiquitin-protein Transferase Activity Receptor Metabolic Process Inorganic Ion Transmembrane Transport Protein Polyubiquitination Protein Monoubiquitination Monoatomic Ion Transmembrane Transport Amyloid-beta Complex Growth Cone Lamellipodium Synaptic Membrane Regulation Of Synapse Organization Regulation Of Response To Calcium Ion	Membrane Transmembrane Transport Monoatomic Ion Transport Zinc Ion Transmembrane Transporter Activity Inorganic Ion Transmembrane Transport Zinc Ion Transport Zinc Ion Transmembrane Transport Metal Ion Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Lysine Transport Potassium Ion Transport Inorganic Cation Transmembrane Transport Protein Binding Plasma Membrane Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport L-lysine Transmembrane Transporter Activity L-histidine Transmembrane Transporter Activity L-histidine Transmembrane Transport Zinc:proton Antiporter Activity Monoamine Transport Intracellular Zinc Ion Homeostasis Monoatomic Cation Transmembrane Transport L-lysine Transmembrane Transport Organic Cation Transport Ion Channel Regulator Activity Renal Water Transport Norepinephrine Transport Positive Regulation Of Sodium Ion Export Across Plasma Membrane Neural Tube Patterning Channel Activity Ammonium Channel Activity Regulation Of Monoatomic Ion Transmembrane Transport Basic Amino Acid Transmembrane Transporter Activity L-arginine Transmembrane Transporter Activity Ammonium Transmembrane Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Response To Zinc Ion Aromatic Amino Acid Transport Zinc Ion Import Into Organelle L-arginine Transmembrane Transport Transport Vesicle Membrane Serotonin Transport Azole Transmembrane Transport Juxtaparanode Region Of Axon Alcohol Dehydrogenase (NADP+) Activity External Side Of Plasma Membrane Water Channel Activity Carbon Dioxide Transport
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