RSPH14 and CNTROB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RSPH14	CNTROB
Description		radial spoke head 14 homolog	centrobin, centriole duplication and spindle assembly protein
Image			No pdb structure
GO Annotations	Cellular Component	Radial Spoke Cytoplasm Cytoskeleton Cilium Motile Cilium Cell Projection	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Ciliary Basal Body
	Molecular Function	Protein Binding	Protein Binding Protein Domain Specific Binding
	Biological Process		Centriole Replication Centrosome Separation Cell Division Regulation Of Cilium Assembly Mitotic Cytokinetic Process
Pathways
Drugs
Diseases
GWAS		Serum parathyroid hormone levels ( 27927781)	Refractive error ( 32231278)
Interacting Genes		40 interacting genes: ABI2 AGAP1 ALS2CL AP1M1 AP2M1 BPIFA1 CCDC102B CDR2 CNTROB COG6 EPS8 FHL3 GABPB1 GOLGA2 JUP KASH5 KIFC3 KRT15 KRT31 KRT40 KRT75 KRT76 LZTS1 MNS1 PIBF1 POLR1C REL RPH3AL RSPH3 SEPTIN12 SMAD4 TCF4 TRAF2 TRIM27 TRIM50 TRIM69 TRIM7 VPS9D1 ZNF474 ZNF629	20 interacting genes: APTX COASY CWF19L2 DAPK1 DUSP29 ELOA EPM2AIP1 GSK3A LYST MCRS1 PELI1 PNKP RAD23A RSPH14 SMARCA2 SYT6 TCEA2 TSC1 TSHZ2 TTC23
Entrez ID		27156	116840
HPRD ID		16136	13991
Ensembl ID		ENSG00000100218	ENSG00000170037
Uniprot IDs		Q9UHP6	Q8N137
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Cytoskeleton Organization Supramolecular Fiber Organization Cytoskeleton Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Organelle Organization Structural Molecule Activity Protein Binding Identical Protein Binding Zonula Adherens Sebaceous Gland Development Clathrin Adaptor Complex Centrosome Separation Positive Regulation Of Actin Nucleation Small GTPase Binding Innate Immune Response Epithelial Cell-cell Adhesion Clathrin Adaptor Activity	Polynucleotide 3'-phosphatase Activity DNA Metabolic Process DNA Repair Positive Regulation Of DNA Repair Damaged DNA Binding Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of TOR Signaling Regulation Of DNA Repair Positive Regulation Of Double-strand Break Repair DNA Damage Response Positive Regulation Of DNA Metabolic Process Cellular Response To Stress DAPK1-calmodulin Complex Macromolecule Metabolic Process Positive Regulation Of Autophagic Cell Death Negative Regulation Of UDP-glucose Catabolic Process Regulation Of Glycogen Metabolic Process Regulation Of TOR Signaling Regulation Of Glycogen Biosynthetic Process Response To Insulin Regulation Of Double-strand Break Repair Memory T Cell Differentiation DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Pantetheine-phosphate Adenylyltransferase Activity
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