GJC1 and TJP3

Number of citations of the paper that reports this interaction (PMID 11557048)
36

Data Source:
HPRD (two hybrid)

		GJC1	TJP3
Gene Name		gap junction protein, gamma 1, 45kDa	tight junction protein 3
Image
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Gap Junction Connexon Complex Intercalated Disc Integral Component Of Membrane	Nucleus Nucleoplasm Tight Junction Apical Plasma Membrane Cell Junction
	Molecular Function	Ion Channel Activity Gap Junction Channel Activity	Protein Binding
	Biological Process	Vasculogenesis Transport Muscle Contraction Cell-cell Junction Assembly Synaptic Transmission Visual Perception Gap Junction Assembly Ion Transmembrane Transport Cell Development Cardiac Muscle Tissue Development Membrane Organization Atrial Cardiac Muscle Cell Action Potential	Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Gap junction assembly Gap junction trafficking and regulation Gap junction trafficking Transmission across Electrical Synapses Electric Transmission Across Gap Junctions
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CNST TJP1 TJP3	5 interactors: CLDN1 FASLG GJC1 INADL TJP1
Entrez ID		10052	27134
HPRD ID		08819	18194
Ensembl ID		ENSG00000182963	ENSG00000105289
Uniprot IDs		P36383	B3KR73 F5H2X0 O95049
PDB IDs		3SHW	3KFV
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Involved In Cell-cell Junction Organization Positive Regulation Of Golgi To Plasma Membrane Protein Transport Response To Magnetism Establishment Of Endothelial Intestinal Barrier Regulation Of Golgi To Plasma Membrane Protein Transport Negative Regulation Of Vascular Permeability Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Establishment Of Endothelial Barrier Hippo Signaling Regulation Of Vascular Permeability Blastocyst Formation Regulation Of Establishment Of Protein Localization To Plasma Membrane Endothelial Cell Development Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Phosphatase Activity Cellular Response To Glucose Stimulus Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Negative Regulation Of Dephosphorylation Execution Phase Of Apoptosis Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Endothelial Cell Differentiation	Cell-cell Junction Organization Cell-cell Junction Assembly Cell Junction Assembly Cell-cell Signaling Involved In Cell-cell Junction Organization Response To Glucose Chemical Homeostasis Cell-cell Signaling Endosomal Lumen Acidification Response To Carbohydrate Response To Magnetism Retinal Cell Programmed Cell Death Necroptotic Signaling Pathway Establishment Of Endothelial Intestinal Barrier Response To Lipopolysaccharide Cellular Chloride Ion Homeostasis Inflammatory Cell Apoptotic Process Homeostatic Process Atrial Cardiac Muscle Cell To AV Node Cell Communication Atrial Cardiac Muscle Cell Action Potential Chloride Ion Homeostasis Response To Molecule Of Bacterial Origin Positive Regulation Of Endothelial Cell Apoptotic Process Negative Regulation Of Vascular Permeability Cell-cell Signaling Involved In Cardiac Conduction Establishment Of Skin Barrier T Cell Apoptotic Process Cell Development Response To Bacterium Regulation Of Water Loss Via Skin Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Intracellular PH Reduction Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cellular Component Assembly PH Reduction Cellular Chemical Homeostasis Gap Junction Assembly Positive Regulation Of ERBB Signaling Pathway Establishment Of Endothelial Barrier Cardiac Muscle Cell Action Potential Involved In Contraction Hippo Signaling Endosome Organization Necroptotic Process Regulation Of Vascular Permeability Multicellular Organismal Development Regulation Of Endothelial Cell Apoptotic Process Anatomical Structure Development Cardiac Muscle Cell Action Potential Cellular Homeostasis Blastocyst Formation Developmental Programmed Cell Death
Tagcloud ?		14days 1mg 3days alters anthracene antral connexin cx cx37 cx43 cx45 dimethylbenz dmba dosed follicle folliculogenesis gap gja1 gja4 junction lean obese obesity ovaries ovotoxicity sesame temporally thereafter wks	adherens atp1a1 atp1b1 bbs1 biogenesis cdh1 cilium cldn2 delineation dynamic fasn foxo1 glycolytic hif1a invaluable junction maturation matured metabolomic monolayer nutrient profound proliferating tight transam transcriptomic tubule uncovered utilizing
Tagcloud (Difference) ?		14days 1mg 3days alters anthracene antral connexin cx cx37 cx43 cx45 dimethylbenz dmba dosed follicle folliculogenesis gap gja1 gja4 lean obese obesity ovaries ovotoxicity sesame temporally thereafter wks	adherens atp1a1 atp1b1 bbs1 biogenesis cdh1 cilium cldn2 delineation dynamic fasn foxo1 glycolytic hif1a invaluable maturation matured metabolomic monolayer nutrient profound proliferating tight transam transcriptomic tubule uncovered utilizing
Tagcloud (Intersection) ?		junction