KRT16 and KRT82

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRT16	KRT82
Description		keratin 16	keratin 82
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Inflammatory Response Cytoskeleton Organization Keratinocyte Differentiation Negative Regulation Of Cell Migration Keratinization Hair Cycle Innate Immune Response Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization Keratinocyte Migration Establishment Of Skin Barrier	Keratinization Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex Non-epidermolytic palmoplantar keratoderma (NEPPK)
GWAS			Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524)
Interacting Genes		53 interacting genes: AIRIM AMOT ARFIP2 C1orf216 CARD9 CCDC146 CCDC17 CCHCR1 CCNC CDK18 CYTH4 DRC4 EPM2AIP1 GNG10 HGS KIFC3 KLC4 KRT1 KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LMO1 LNX1 MBD3 PKN1 POLL PPP1R18 PRKAA2 PRPH PUS10 SEMA4C SGF29 SMARCD1 SMARCE1 SNAPIN TCHP TSG101 TTC23 TXLNB USHBP1	15 interacting genes: COL8A1 HGS HOXA1 KRT15 KRT16 KRT19 KRT27 KRT31 KRT33B KRT34 KRT35 KRT36 KRT40 PLSCR4 VAC14
Entrez ID		3868	3888
HPRD ID		01018	03048
Ensembl ID		ENSG00000186832	ENSG00000161850
Uniprot IDs		P08779	Q9NSB4
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Keratin Filament Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Protein Binding Cytosol	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Supramolecular Fiber Organization Anatomical Structure Morphogenesis Cytoskeleton Organization Cytoskeleton Cell Differentiation Organelle Organization Structural Constituent Of Cytoskeleton Cellular Developmental Process Epidermis Development Extracellular Exosome Hair Cycle Developmental Process Cytosol Semicircular Canal Formation PAS Complex Collagen Type VIII Trimer Abducens Nerve Formation Optokinetic Behavior Terminal Web ESCRT-0 Complex Calcium Activated Phosphatidylserine Scrambling Tissue Development Phagocytic Vesicle Lumen Calcium Activated Phosphatidylcholine Scrambling Calcium Activated Phospholipid Scrambling
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