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KRT16 and GNG10
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
KRT16
GNG10
Description
keratin 16
G protein subunit gamma 10
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cornified Envelope
Nucleus
Cytosol
Cytoskeleton
Intermediate Filament
Keratin Filament
Extracellular Exosome
Heterotrimeric G-protein Complex
Plasma Membrane
Membrane
Molecular Function
Structural Molecule Activity
Structural Constituent Of Cytoskeleton
Protein Binding
Structural Constituent Of Skin Epidermis
GTPase Activity
Protein Binding
G-protein Beta-subunit Binding
Biological Process
Morphogenesis Of An Epithelium
Inflammatory Response
Cytoskeleton Organization
Keratinocyte Differentiation
Negative Regulation Of Cell Migration
Keratinization
Hair Cycle
Innate Immune Response
Intermediate Filament Cytoskeleton Organization
Intermediate Filament Organization
Keratinocyte Migration
Establishment Of Skin Barrier
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Pathways
Keratinization
Formation of the cornified envelope
Activation of G protein gated Potassium channels
Glucagon signaling in metabolic regulation
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
G beta:gamma signalling through BTK
G beta:gamma signalling through CDC42
Extra-nuclear estrogen signaling
GPER1 signaling
ADORA2B mediated anti-inflammatory cytokines production
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Zinc
Zinc acetate
Diseases
Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
Non-epidermolytic palmoplantar keratoderma (NEPPK)
GWAS
Interacting Genes
53 interacting genes:
AIRIM
AMOT
ARFIP2
C1orf216
CARD9
CCDC146
CCDC17
CCHCR1
CCNC
CDK18
CYTH4
DRC4
EPM2AIP1
GNG10
HGS
KIFC3
KLC4
KRT1
KRT6C
KRT71
KRT72
KRT73
KRT74
KRT76
KRT77
KRT78
KRT79
KRT8
KRT80
KRT81
KRT82
KRT83
KRT85
KRT86
LMO1
LNX1
MBD3
PKN1
POLL
PPP1R18
PRKAA2
PRPH
PUS10
SEMA4C
SGF29
SMARCD1
SMARCE1
SNAPIN
TCHP
TSG101
TTC23
TXLNB
USHBP1
8 interacting genes:
GNB1
GNB2
GNB4
KRT16
KRT31
KRT34
KRT38
TCF4
Entrez ID
3868
2790
HPRD ID
01018
10374
Ensembl ID
ENSG00000186832
ENSG00000242616
Uniprot IDs
P08779
P50151
PDB IDs
Enriched GO Terms of Interacting Partners
?
Intermediate Filament Organization
Keratin Filament
Structural Constituent Of Skin Epidermis
Keratinization
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Intermediate Filament
Supramolecular Fiber Organization
Cytoskeleton Organization
Organelle Organization
Protein Binding
Cytosol
Structural Constituent Of Skin Epidermis
Intermediate Filament Organization
Intermediate Filament Cytoskeleton Organization
Keratin Filament
Intermediate Filament-based Process
Signaling Receptor Complex Adaptor Activity
Heterotrimeric G-protein Complex
Intermediate Filament
Structural Molecule Activity
Morphogenesis Of An Epithelium
Epithelial Cell Differentiation
Tissue Morphogenesis
Epidermis Development
Supramolecular Fiber Organization
Extracellular Exosome
GTPase Binding
Protein-containing Complex Binding
Lysosomal Membrane
Cytoskeleton Organization
Structural Constituent Of Cytoskeleton
Developmental Process
Beta-catenin-TCF7L2 Complex
Cytosol
Cell Differentiation
TFIIB-class Transcription Factor Binding
Cytoskeleton
Keratinocyte Migration
Anatomical Structure Morphogenesis
Tissue Development
G Protein-coupled Receptor Signaling Pathway
Cellular Developmental Process
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Beta-catenin-TCF Complex
Hair Cycle
Synapse
Cellular Response To Catecholamine Stimulus
GTPase Activity
Cellular Response To Prostaglandin E Stimulus
Response To Catecholamine
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Photoreceptor Disc Membrane
G Protein-coupled Dopamine Receptor Signaling Pathway
Cellular Response To Prostaglandin Stimulus
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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