GK and GPD1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GK	GPD1
Gene Name		glycerol kinase	glycerol-3-phosphate dehydrogenase 1 (soluble)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrial Outer Membrane Cytosol Extracellular Vesicular Exosome	Mitochondrion Cytosol Glycerol-3-phosphate Dehydrogenase Complex Extracellular Vesicular Exosome
	Molecular Function	Glycerol Kinase Activity Protein Binding ATP Binding	Glycerol-3-phosphate Dehydrogenase [NAD+] Activity Glycerol-3-phosphate Dehydrogenase Activity Protein Homodimerization Activity NAD Binding
	Biological Process	Glycerol Metabolic Process Triglyceride Metabolic Process Phosphorylation Triglyceride Biosynthetic Process Glycerol Catabolic Process Glucose Homeostasis Cellular Lipid Metabolic Process Small Molecule Metabolic Process Glycerol-3-phosphate Biosynthetic Process	Gluconeogenesis NADH Oxidation Glycerophosphate Shuttle Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Triglyceride Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Glycolytic Process Glycerol-3-phosphate Catabolic Process Glycerophospholipid Biosynthetic Process Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor
Pathways		Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Triglyceride Biosynthesis	Synthesis of PA Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Phospholipid metabolism Glycerophospholipid biosynthesis Triglyceride Biosynthesis
Drugs			NADH
Diseases
GWAS
Protein-Protein Interactions		11 interactors: AOX1 APCS CLPTM1L CYP3A4 EIF4G1 FBXO28 GPD1 IPO13 NR4A1 OPLAH RXRA	3 interactors: GK MDH1 PTN
Entrez ID		2710	2819
HPRD ID		08363	00714
Ensembl ID		ENSG00000198814	ENSG00000167588
Uniprot IDs		B4DH54 P32189	P21695
PDB IDs			1WPQ 1X0V 1X0X
Enriched GO Terms of Interacting Partners?		Vitamin Metabolic Process Regulation Of Translational Initiation Glycerophosphate Shuttle Cellular Response To Organic Cyclic Compound Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Positive Regulation Of Translational Initiation By Iron Negative Regulation Of Exo-alpha-sialidase Activity Steroid Hormone Mediated Signaling Pathway Cellular Nitrogen Compound Metabolic Process Alkaloid Catabolic Process Hormone-mediated Signaling Pathway Xenobiotic Metabolic Process Small Molecule Metabolic Process Cellular Response To Xenobiotic Stimulus Cellular Response To Hormone Stimulus Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Response To Xenobiotic Stimulus Vitamin B6 Metabolic Process Glycerol-3-phosphate Catabolic Process Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Monoterpenoid Metabolic Process NADH Oxidation Peroxisome Proliferator Activated Receptor Signaling Pathway Calcitriol Biosynthetic Process From Calciol Cellular Response To Steroid Hormone Stimulus Negative Regulation Of Monocyte Differentiation Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Response To Stimulus Regulation Of Branching Involved In Prostate Gland Morphogenesis Alkaloid Metabolic Process Steroid Metabolic Process Glycerol-3-phosphate Metabolic Process Response To Organic Cyclic Compound Cellular Response To Organic Substance Positive Regulation Of Glycolytic Process Negative Regulation Of Glycoprotein Metabolic Process Regulation Of Translation Oxidative Demethylation Chaperone-mediated Protein Complex Assembly Vitamin D Metabolic Process Muscle Organ Development Response To Hormone Regulation Of Monocyte Differentiation Positive Regulation Of Translational Initiation Endothelial Cell Chemotaxis Negative Regulation Of Acute Inflammatory Response Cellular Lipid Metabolic Process	Glycerol-3-phosphate Biosynthetic Process Cellular Carbohydrate Metabolic Process Glycerol Catabolic Process Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Malate Metabolic Process Glycerol-3-phosphate Metabolic Process NADH Metabolic Process Oxaloacetate Metabolic Process Cellular Carbohydrate Catabolic Process Glycerol Metabolic Process Tricarboxylic Acid Cycle Organophosphate Metabolic Process Triglyceride Biosynthetic Process Carbohydrate Metabolic Process Citrate Metabolic Process Bone Mineralization NAD Metabolic Process Alcohol Catabolic Process Tricarboxylic Acid Metabolic Process Gluconeogenesis Aerobic Respiration Hexose Biosynthetic Process Biomineral Tissue Development Nicotinamide Nucleotide Metabolic Process Dicarboxylic Acid Metabolic Process Triglyceride Metabolic Process Neutral Lipid Metabolic Process Positive Regulation Of Cell Division Learning Glucose Metabolic Process Carbohydrate Biosynthetic Process Carbohydrate Catabolic Process
Tagcloud ?		cask channels clustering coclusters coimmunoprecipitates colocalizes constituent cooh enzymatic fact gkap guanylate heterologous homology isolation junction lin maguk nh2 obscure organization pdz postsynaptic psd sap90 sh3 synaptic termed zo	abhd5 agpat2 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Difference) ?		cask channels clustering coclusters coimmunoprecipitates colocalizes constituent cooh enzymatic fact gkap guanylate heterologous homology isolation junction lin maguk nh2 obscure organization pdz postsynaptic psd sap90 sh3 synaptic termed zo	abhd5 agpat2 anomaly atgl cgi ctgm dgat1 diverge enteropathy glycerol hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Intersection) ?		gk