LYPD3 and RB1CC1

Number of citations of the paper that reports this interaction (PubMedID 25640309)
0

Data Source:
BioGRID (two hybrid)

		LYPD3	RB1CC1
Description		LY6/PLAUR domain containing 3	RB1 inducible coiled-coil 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane Side Of Membrane	Phagophore Assembly Site Autophagosome Membrane Nucleus Cytoplasm Lysosome Vacuole Endoplasmic Reticulum Membrane Cytosol Organelle Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex
	Molecular Function	Laminin Binding	Protein Binding Protein Kinase Binding Protein-membrane Adaptor Activity Molecular Adaptor Activity
	Biological Process	Cell-matrix Adhesion Negative Regulation Of Smooth Muscle Cell Apoptotic Process	Autophagosome Assembly Autophagy Of Mitochondrion Pexophagy Liver Development Autophagy Apoptotic Process Heart Development Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Ribophagy Piecemeal Microautophagy Of The Nucleus Negative Regulation Of Apoptotic Process Innate Immune Response Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Defense Response To Virus Reticulophagy Glycophagy Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Macroautophagy
Drugs
Diseases
GWAS		Cotinine glucuronidation ( 25293881)	Body size at age 10 ( 32376654) Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		17 interacting genes: AGR2 AGR3 AURKA BAG4 BRMS1 CASP8 CHEK2 CTRB1 ERBB2 IGF1R LSP1 PALB2 PPM1D PTPRJ RB1CC1 SMAD4 STK11	35 interacting genes: ATG12 AZI2 BAP1 BLID CALCOCO2 COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MECOM MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 THRSP UBC UMPS VAPA VHL VPS45 WIF1
Entrez ID		27076	9821
HPRD ID		10783	06019
Ensembl ID		ENSG00000124466	ENSG00000023287
Uniprot IDs		B2RBR3 O95274	Q8TDY2
PDB IDs		6IOM 6ION	6DCE 6GMA 7CZG 7CZM 7D0E 7EA2 7EAA 8SOI 8SQZ 8SRM 8W6B 8YFK 8YFL 8YFM 8YFN 9C82 9D34
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Signal Transduction Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Cell Projection Organization Protein Autophosphorylation Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Response To Glycoside Plasma Membrane Bounded Cell Projection Organization Apoptotic Process Negative Regulation Of Programmed Cell Death Apoptotic Signaling Pathway Protein Phosphorylation G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Anoikis Cell Death Positive Regulation Of Cell Communication Positive Regulation Of Signaling Programmed Cell Death Cell Cycle G2/M Phase Transition Phosphorylation Negative Regulation Of Signal Transduction Dystroglycan Binding Carbohydrate Homeostasis Glucose Homeostasis Response To Stress Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Cell Population Proliferation Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Component Organization Negative Regulation Of Intracellular Signal Transduction Protein Dephosphorylation Autophagosome Assembly Protein Kinase Activity Heart Development Positive Regulation Of Metabolic Process Autophagosome Organization Signal Transduction By P53 Class Mediator Negative Regulation Of Apoptotic Process Extrinsic Apoptotic Signaling Pathway Ubiquitin Protein Ligase Binding Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Mitogen-activated Protein Kinase Binding Regulation Of Signal Transduction By P53 Class Mediator Phosphate-containing Compound Metabolic Process Regulation Of Growth	Autophagosome Membrane Autophagosome Cellular Response To Nitrogen Starvation Autophagosome Maturation Phosphatidylethanolamine Binding GABA Receptor Binding Autophagy Of Mitochondrion Macroautophagy Autophagosome Assembly Autophagosome Organization Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Beta-tubulin Binding Signal Complex Assembly Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein-containing Complex Disassembly Mitophagy Glycophagy Epidermal Growth Factor Receptor Signaling Pathway Apoptotic Process Ubiquitin Protein Ligase Binding Autophagy Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Tag Activity Vacuole Organization Regulation Of Autophagosome Maturation Programmed Cell Death Cell Death ERBB Signaling Pathway Protein Localization To Endoplasmic Reticulum Positive Regulation Of Proteolysis Glycogen Catabolic Process Regulation Of Proteolysis Histone H3 Methyltransferase Activity Catabolic Process Polysaccharide Catabolic Process Regulation Of Macrophage Chemotaxis Cellular Response To Fluid Shear Stress Neurotransmitter Receptor Regulator Activity Orotidine-5'-phosphate Decarboxylase Activity Orotate Phosphoribosyltransferase Activity Nucleate Erythrocyte Differentiation Thrombocyte Differentiation Golgi Membrane Phospholipid Binding Heparosan-N-sulfate-glucuronate 5-epimerase Activity Meiotic Joint Molecule Formation DNA Recombinase Auxiliary Factor Complex Recombinase Activator Activity Meiotic Strand Invasion Involved In Reciprocal Meiotic Recombination Histone H3K4 Dimethyltransferase Activity
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