FOXB1 and COPB1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		FOXB1	COPB1
Description		forkhead box B1	coat protein complex I subunit beta 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle COPI-coated Vesicle Membrane Secretory Granule Membrane Cytoplasmic Vesicle Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Structural Molecule Activity Protein Binding
	Biological Process	Urogenital System Development Somitogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Axon Target Recognition Lactation Visual Learning Anatomical Structure Morphogenesis Spinal Cord Development Mammillary Body Development Thalamus Development Hypothalamus Cell Migration Telencephalon Cell Migration Cell Differentiation Midbrain Development Floor Plate Development Negative Regulation Of Neuron Apoptotic Process Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Mammillothalamic Axonal Tract Development Mammary Gland Lobule Development Inferior Colliculus Development Cell Migration In Diencephalon	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport
Pathways			Neutrophil degranulation COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Asthma ( 31959851) Night sleep phenotypes ( 27126917)	HDL cholesterol ( 26780889) HDL cholesterol levels ( 28334899 32203549) Height ( 31562340) High chromosomal aberration frequency (total) ( 31586183) Hip circumference adjusted for BMI ( 34021172) Vitamin D levels ( 25208829)
Interacting Genes		8 interacting genes: COPB1 KRT31 KRT40 KRTAP10-3 KRTAP10-8 NOTCH2NLA PHF5A TRIM27	46 interacting genes: ADAM19 ANO1 APP ARCN1 ARF1 BCAR1 COPE COPG1 COPG2 DSCR9 ERBIN FOXB1 GORAB GRB2 GTPBP4 HLA-DPB1 HLA-G ID1 IRAK3 KCNK3 KDELR1 KIAA1328 LINC00839 LZTS1 LZTS2 NUB1 PDGFRB PRKCE PTEN RGS2 RGS4 RHOQ RNF10 SERTAD1 SNTA1 SPTBN1 TANK TAPBP TMED10 TRIM37 TTYH2 UBC UBQLN4 VPS18 WBP2 XRCC6
Entrez ID		27023	1315
HPRD ID		07017	02981
Ensembl ID		ENSG00000171956	ENSG00000129083
Uniprot IDs		Q99853	P53618
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Structural Molecule Activity Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Supramolecular Fiber Organization	COPI-coated Vesicle Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum COPI Vesicle Coat COPI-coated Vesicle Transport Vesicle Golgi Vesicle Transport Vesicle-mediated Transport Golgi Membrane Negative Regulation Of Glycine Import Across Plasma Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Establishment Of Protein Localization Positive Regulation Of Reactive Oxygen Species Metabolic Process Golgi Apparatus Regulation Of Actin Cytoskeleton Organization Regulation Of Biological Quality Cytoplasmic Vesicle Regulation Of Actin Filament-based Process Endoplasmic Reticulum-Golgi Intermediate Compartment Lumenal Side Of Endoplasmic Reticulum Membrane Regulation Of Cytoskeleton Organization Endoplasmic Reticulum Membrane Positive Regulation Of Excitatory Postsynaptic Potential Protein Transport Negative Regulation Of Organ Growth Intra-Golgi Vesicle-mediated Transport Peptide Antigen Binding Regulation Of Protein Metabolic Process Plasma Membrane Regulation Of Innate Immune Response Signaling Receptor Activator Activity Positive Regulation Of Macromolecule Biosynthetic Process Neuron Projection Organization Cytoplasm Positive Regulation Of Metabolic Process Modulation Of Chemical Synaptic Transmission Positive Regulation Of Biosynthetic Process Positive Regulation Of Multicellular Organismal Process Regulation Of Nervous System Process Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Cytokine Production Regulation Of Cellular Component Organization Membrane Regulation Of Supramolecular Fiber Organization Regulation Of Reactive Oxygen Species Metabolic Process Cellular Localization Regulation Of Intracellular Signal Transduction Intracellular Protein Localization Intracellular Protein Transport ER To Golgi Transport Vesicle Membrane Positive Regulation Of Tolerance Induction
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