RNU1-1 and GEMIN2

Number of citations: 111 (PubMedID 23221635)
Data Source: BioGRID (affinity chromatography technology, unspecified method)

		RNU1-1	GEMIN2
Name		RNA, U1 small nuclear 1	gem nuclear organelle associated protein 2
Structure		No pdb structure
GO Annotations	Cellular Component	None	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies
	Molecular Function	None	Protein Binding
	Biological Process	None	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Protein-containing Complex Assembly
Pathways		None	snRNP Assembly SARS-CoV-2 modulates host translation machinery
GWAS		No GWAS studies recorded	Vitamin D levels ( 28757204 )
Novel Interactors		None recorded	1 novel interactors: AKAP6
Interacting Genes		12 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GEMIN8 PRPF39 RAE1 SMN1 SND1 STRAP	33 interacting genes: BEND7 DDX20 DHX9 FBXO7 GEMIN5 HOXD10 IKBKG INCA1 KPNA6 MEOX1 MTNR1A NUFIP1 PAX6 PSMB1 RN7SL1 RNU1-1 RNU2-1 RPP14 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SPG21 SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2
Entrez ID		26871	8487
HPRD ID		Not available	03999
Ensembl ID		ENSG00000206652	ENSG00000092208
Uniprot IDs		Not available	A0A8J9FJK1 A0A8J9FN78 O14893
PDB IDs		Not available	2LEH 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU
GO Terms Enriched among Interactors		SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies Spliceosomal SnRNP Assembly Protein-RNA Complex Assembly MRNA Metabolic Process RNA Splicing MRNA Processing RNA Processing RNA Metabolic Process Protein-containing Complex Assembly Nucleic Acid Metabolic Process Protein-containing Complex Organization Nuclear Body RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Cellular Component Assembly Spliceosomal Complex Assembly Nucleus Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome RNA Binding Nucleoplasm Cytosol Cytoplasm SMN-Gemin2 Complex RNAi Effector Complex Sm-like Protein Family Complex Cajal Body U2 SnRNP Binding U4atac SnRNA Binding Pre-mRNA 5'-splice Site Binding RISC Complex Binding Dense Body Commitment Complex Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery U4 SnRNA Binding RNA Polymerase II Transcription Repressor Complex U1 SnRNA Binding MRNA 5'-splice Site Recognition SnRNA Binding MiRNA Catabolic Process Ribonucleoside Triphosphate Phosphatase Activity RNA 7-methylguanosine Cap Binding	RNA Splicing MRNA Processing SMN-Sm Protein Complex Protein-RNA Complex Assembly RNA Splicing, Via Transesterification Reactions RNA Processing MRNA Metabolic Process Spliceosomal SnRNP Assembly RNA Metabolic Process MRNA Splicing, Via Spliceosome U1 SnRNP Spliceosomal Complex Assembly RNA Binding U2 SnRNP SMN Complex U4 SnRNP Nucleoplasm Nucleic Acid Metabolic Process Gemini Of Cajal Bodies Regulation Of MRNA Processing Small Nuclear Ribonucleoprotein Complex Protein-containing Complex Assembly Spliceosomal Complex U5 SnRNP Commitment Complex Regulation Of MRNA Splicing, Via Spliceosome PICln-Sm Protein Complex Protein-containing Complex Organization Nucleobase-containing Compound Metabolic Process 7-methylguanosine Cap Hypermethylation MRNA Binding Catalytic Step 2 Spliceosome U4/U6 X U5 Tri-snRNP Complex Regulation Of RNA Splicing Methylosome Sequence-specific MRNA Binding Regulation Of MRNA Metabolic Process Nucleus U2-type Prespliceosome Nuclear Body DNA-templated Transcription Termination Precatalytic Spliceosome Ribonucleoprotein Complex Regulation Of Alternative MRNA Splicing, Via Spliceosome Tertiary Granule Nucleic Acid Binding Cellular Response To Cytokine Stimulus U2-type Prespliceosome Assembly U12-type Spliceosomal Complex Cytoplasmic Ribonucleoprotein Granule