RNU1-1 and PRPF39

Number of citations of the paper that reports this interaction (PubMedID 29051543)
77

Data Source:
BioGRID (unspecified method)

		RNU1-1	PRPF39
Description		RNA, U1 small nuclear 1	pre-mRNA processing factor 39
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Commitment Complex Nucleus U1 SnRNP U2-type Prespliceosome
	Molecular Function		Protein Binding Pre-mRNA 5'-splice Site Binding
	Biological Process		MRNA 5'-splice Site Recognition RNA Processing MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS			Lead levels ( 26025379)
Interacting Genes		12 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GEMIN8 PRPF39 RAE1 SMN1 SND1 STRAP	14 interacting genes: BANP CEBPA DHX30 DMRTB1 GTSE1 LARP4 MBNL1 PRRC2B QKI RBM22 RNU1-1 SF1 TOLLIP TRNAU1AP
Entrez ID		26871	55015
HPRD ID			17913
Ensembl ID		ENSG00000206652	ENSG00000185246
Uniprot IDs			Q86UA1
PDB IDs
Enriched GO Terms of Interacting Partners?		SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies Spliceosomal SnRNP Assembly Protein-RNA Complex Assembly MRNA Metabolic Process RNA Splicing MRNA Processing RNA Processing RNA Metabolic Process Protein-containing Complex Assembly Nucleic Acid Metabolic Process Protein-containing Complex Organization Nuclear Body RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Cellular Component Assembly Spliceosomal Complex Assembly Nucleus Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome RNA Binding Nucleoplasm Cytosol Cytoplasm SMN-Gemin2 Complex RNAi Effector Complex Sm-like Protein Family Complex Cajal Body U2 SnRNP Binding U4atac SnRNA Binding Pre-mRNA 5'-splice Site Binding RISC Complex Binding Dense Body Commitment Complex Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery U4 SnRNA Binding RNA Polymerase II Transcription Repressor Complex U1 SnRNA Binding MRNA 5'-splice Site Recognition SnRNA Binding MiRNA Catabolic Process Ribonucleoside Triphosphate Phosphatase Activity RNA 7-methylguanosine Cap Binding	RNA Binding Nucleic Acid Binding Protein Localization To Endosome Cytoplasmic Stress Granule MRNA Cis Splicing, Via Spliceosome RNA Splicing Erythrocyte Apoptotic Process Macrophage Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding MRNA Processing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Internal N(7)-methylguanine-containing RNA Reader Activity
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