OSTM1 and CLCN7

Number of citations of the paper that reports this interaction (PMID 16525474)
41

Data Source:
HPRD (in vivo)

		OSTM1	CLCN7
Gene Name		osteopetrosis associated transmembrane protein 1	chloride channel, voltage-sensitive 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Lysosomal Membrane Cytosol Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Lysosomal Membrane Membrane Integral Component Of Membrane Cytoplasmic Vesicle
	Molecular Function		Voltage-gated Chloride Channel Activity Chloride Channel Activity ATP Binding Antiporter Activity
	Biological Process	Osteoclast Differentiation Ion Transmembrane Transport Transmembrane Transport	Transport Response To PH Ion Transmembrane Transport Regulation Of Anion Transport Transmembrane Transport Chloride Transmembrane Transport
Pathways		Ion channel transport Stimuli-sensing channels	Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CLCN7 GPSM1 LIG4 RGS17 RGS19 RGS20	2 interactors: OSTM1 PACS1
Entrez ID		28962	1186
HPRD ID		09628	04103
Ensembl ID		ENSG00000081087	ENSG00000103249
Uniprot IDs		Q86WC4	P51798
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway DNA Ligation Involved In DNA Recombination Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Regulation Of Catalytic Activity Lagging Strand Elongation Pro-B Cell Differentiation Positive Regulation Of Hydrolase Activity Negative Regulation Of Signal Transduction Establishment Of Integrated Proviral Latency Negative Regulation Of Signaling Establishment Of Viral Latency Immunoglobulin V(D)J Recombination Regulation Of Signal Transduction DNA Ligation Involved In DNA Repair T Cell Receptor V(D)J Recombination Lymphoid Progenitor Cell Differentiation Regulation Of Signaling DNA Ligation Nucleotide-excision Repair, DNA Gap Filling Cellular Response To Lithium Ion Positive Regulation Of Catalytic Activity Single Strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Isotype Switching V(D)J Recombination DNA Strand Elongation Involved In DNA Replication Response To Lithium Ion DNA Strand Elongation Response To X-ray Somatic Recombination Of Immunoglobulin Gene Segments Response To PH Somatic Diversification Of Immunoglobulins Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response B Cell Activation Involved In Immune Response Response To Gamma Radiation Neuron Apoptotic Process	Protein Targeting To Golgi Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Regulation Of Defense Response To Virus By Virus Protein Localization To Golgi Apparatus Protein Targeting To Plasma Membrane Osteoclast Differentiation Intra-Golgi Vesicle-mediated Transport Establishment Of Protein Localization To Plasma Membrane Regulation Of Defense Response To Virus
Tagcloud ?		anhydrase arthritis carbonic cathepsin chalcone clcn7 destructive elucidate expressions fos gab2 modulating multinucleated nfatc1 osteoclast osteoclastogenesis osteoclasts osteoporosis periodontitis pit prenylated rankl raw264 resorption structurally suppress tcirg traf6 xanthohumol	apply asp complementation complementing ddx1 disequilibrium erb ercc1 erythroblastic exo1 exonuclease gwas helicase inconsistent nominal perfect phosphoprotein prerequisite reexamined replicate replicating rs2844484 rs2857602 spp1 stringent swedish tmc6 tmc8 underscore
Tagcloud (Difference) ?		anhydrase arthritis carbonic cathepsin chalcone destructive elucidate expressions fos gab2 modulating multinucleated nfatc1 osteoclast osteoclastogenesis osteoclasts osteoporosis periodontitis pit prenylated rankl raw264 resorption structurally suppress tcirg traf6 xanthohumol	apply asp complementation complementing ddx1 disequilibrium erb ercc1 erythroblastic exo1 exonuclease gwas helicase inconsistent nominal perfect phosphoprotein prerequisite reexamined replicate replicating rs2844484 rs2857602 spp1 stringent swedish tmc6 tmc8 underscore
Tagcloud (Intersection) ?		clcn7