GCSH and ING5

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GCSH	ING5
Gene Name		glycine cleavage system protein H (aminomethyl carrier)	inhibitor of growth family, member 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Glycine Cleavage Complex	Nucleus Nucleoplasm MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Aminomethyltransferase Activity Enzyme Binding	Chromatin Binding Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	Glycine Catabolic Process Glycine Decarboxylation Via Glycine Cleavage System Methylation	DNA Replication Chromatin Organization Transcription, DNA-templated Protein Acetylation Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Positive Regulation Of Apoptotic Signaling Pathway
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ING5 NMI SFI1 ZBTB16	34 interactors: APC APLP1 ARFIP2 BARD1 C3orf62 CCDC33 CCDC67 CDCA7L CDKN1A CEP44 EP300 FAM118B GCSH HAP1 HGS HTT ICA1 IKZF3 JADE2 KIAA1377 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 PCM1 PRMT5 SMARCE1 TADA3 TAF1D TP53 VIM
Entrez ID		2653	84289
HPRD ID		01998	16348
Ensembl ID		ENSG00000140905	ENSG00000168395
Uniprot IDs		P23434	Q8WYH8
PDB IDs			3C6W
Enriched GO Terms of Interacting Partners?		Positive Regulation Of NK T Cell Differentiation Male Germ-line Stem Cell Asymmetric Division	Mitotic Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Chromosome Organization Cell Cycle Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Cell Cycle Regulation Of Tubulin Deacetylation Histone Acetylation Mitotic Cell Cycle Phase Transition Internal Peptidyl-lysine Acetylation Cell Cycle Phase Transition Peptidyl-lysine Acetylation Cytoplasmic Microtubule Organization Chromatin Organization Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Gene Expression Cell Cycle Arrest Histone H3 Acetylation Regulation Of Protein Deacetylation Circadian Rhythm Chromatin Modification Stress-induced Premature Senescence Histone Modification Cell Aging Apoptotic Process Negative Regulation Of Gene Expression Tissue Development Central Nervous System Development Regulation Of Mitotic Cell Cycle Negative Regulation Of Biosynthetic Process Anatomical Structure Development Regulation Of Protein Metabolic Process Mitotic Cell Cycle Arrest Programmed Cell Death Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Intracellular Transport Regulation Of Cellular Localization Regulation Of Cell Cycle Phase Transition Cell Death Death Nervous System Development Epithelium Development Determination Of Adult Lifespan See more
Tagcloud ?		acetylcysteine alleviated amd atf4 atral bip chop degeneration deleterious detrimental etiologies gadd34 ho macular meanwhile nac nrf2 overproduction photoreceptor pigment resident retinal ribose ros rpe salubrinal stargardt tolerate trigger	acetylates acetyllysine bonding bromodomain brpf1 calculate directs discrete energies finger h2a h2ak5ac h2b h3k14ac h4k12ac hat heaf6 histones monocytic moz outline perturbation phd pocket quaternary selects tails titration translationally
Tagcloud (Difference) ?		acetylcysteine alleviated amd atf4 atral bip chop degeneration deleterious detrimental etiologies gadd34 ho macular meanwhile nac nrf2 overproduction photoreceptor pigment resident retinal ribose ros rpe salubrinal stargardt tolerate trigger	acetylates acetyllysine bonding bromodomain brpf1 calculate directs discrete energies finger h2a h2ak5ac h2b h3k14ac h4k12ac hat heaf6 histones monocytic moz outline perturbation phd pocket quaternary selects tails titration translationally
Tagcloud (Intersection) ?