PGD

Gene Name		phosphogluconate dehydrogenase
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Extracellular Vesicular Exosome
	Molecular Function	Phosphogluconate Dehydrogenase (decarboxylating) Activity NADP Binding
	Biological Process	Carbohydrate Metabolic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Oxidative Branch Pathogenesis Pentose Biosynthetic Process D-gluconate Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates Pentose phosphate pathway (hexose monophosphate shunt)
Drugs
Diseases
GWAS		Hepatocellular carcinoma ( 20676096)
Protein-protein Interactions		4 interactors: CDK4 GBE1 LSM8 TERF1
Entrez ID		5226
HPRD ID		01391
Ensembl ID		ENSG00000142657
Uniprot IDs		P52209
PDB IDs		2JKV 4GWG 4GWK
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Telomere Maintenance Via Telomere Shortening Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Negative Regulation Of Telomere Maintenance Via Telomerase Replicative Cell Aging Negative Regulation Of Telomerase Activity Positive Regulation Of Cell Size Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Mitotic Cell Cycle Regulation Of Telomere Maintenance Via Telomerase Cell Division Negative Regulation Of Cell Cycle Positive Regulation Of Microtubule Polymerization Regulation Of Cell Cycle Process Regulation Of Telomerase Activity Response To Drug Regulation Of Telomere Maintenance Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death RNA-dependent DNA Replication Positive Regulation Of Cell Death Negative Regulation Of Cell Cycle Arrest Negative Regulation Of DNA Biosynthetic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Lead Ion Glycogen Biosynthetic Process Response To Hyperoxia Mitotic Cell Cycle Process Regulation Of Microtubule Polymerization Chromatin Organization Telomere Maintenance Via Telomere Lengthening Response To Testosterone Mitotic Cell Cycle Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Cellular Polysaccharide Biosynthetic Process Mitotic Spindle Checkpoint Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Polysaccharide Biosynthetic Process
Tagcloud ?		a2 achieved actions advances bk1 bk2 bk3 bk4 bradykinin characterization detail diverse ep1 ep2 ep3 ep4 exert hypertension pge prostacyclin prostaglandin prostanoid prostanoids remarkable reviewed subtypes thromboxane versatile