PGD and LINC00632

Number of citations of the paper that reports this interaction (PubMedID 36527092)
63

Data Source:
BioGRID (unspecified method)

		PGD	LINC00632
Description		phosphogluconate dehydrogenase	long intergenic non-protein coding RNA 632
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Phosphogluconate Dehydrogenase (decarboxylating) Activity Oxidoreductase Activity Carbohydrate Binding Carboxylic Acid Binding NADP Binding
	Biological Process	Pentose-phosphate Shunt NADP+ Metabolic Process NADPH Regeneration Pentose-phosphate Shunt, Oxidative Branch Pentose Biosynthetic Process D-gluconate Metabolic Process
Pathways		Pentose phosphate pathway NFE2L2 regulates pentose phosphate pathway genes
Drugs		Gadopentetic acid Dacarbazine Ketotifen 6-phospho-D-gluconic acid Nicotinamide 8-bromo-adenine dinucleotide phosphate
Diseases
GWAS		Hemoglobin ( 32888494) Hepatocellular carcinoma ( 20676096) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: CDC42 CDK4 GBE1 LINC00632 LINC01554 LSM8 OGT TERF1	37 interacting genes: ACO2 ACTR2 ANP32A ANXA6 ARF3 ASPH CTSB DYNC1LI2 ELAVL1 GDI1 GDI2 GNB1 HSPE1 ITGA3 LAP3 LGALS3 LMAN1 MDH2 MXRA7 PAICS PFKP PGD PGRMC1 PGRMC2 PSMA1 PXN RAB1B RECQL RPLP0 RPN2 RRAS2 SF1 STMN1 TGFBI TPM1 TUBA1C UGDH
Entrez ID		5226	286411
HPRD ID		01391
Ensembl ID		ENSG00000142657	ENSG00000203930
Uniprot IDs		B4E2U0 P52209
PDB IDs		2JKV 4GWG 4GWK 5UQ9
Enriched GO Terms of Interacting Partners?		Glycosyltransferase Activity 1,4-alpha-glucan Branching Enzyme Activity Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Glycosylation-dependent Protein Binding Dolichyl-phosphate Beta-glucosyltransferase Activity GBD Domain Binding Storage Vacuole Cyclin D1-CDK4 Complex Cyclin D3-CDK4 Complex Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication	Extracellular Exosome Focal Adhesion Rab GDP-dissociation Inhibitor Activity
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