TRDMT1 and TBC1D2B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		TRDMT1	TBC1D2B
Description		tRNA aspartic acid methyltransferase 1	TBC1 domain family member 2B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	RNA Binding Methyltransferase Activity TRNA Methyltransferase Activity TRNA (cytidine-5-)-methyltransferase Activity Transferase Activity	GTPase Activator Activity Protein Binding
	Biological Process	TRNA Modification TRNA Processing TRNA Methylation Methylation TRNA Stabilization	Endocytosis Regulation Of Cilium Assembly
Pathways		tRNA modification in the nucleus and cytosol
Drugs		Pentamidine S-adenosyl-L-homocysteine Glycerin
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Telomere length ( 24478790)	Diffusing capacity of carbon monoxide ( 30694715) Eyebrow thickness ( 26926045) Metabolite levels ( 23823483)
Interacting Genes		14 interacting genes: APP COPS6 DDX24 EEF1A1 GBE1 LRIF1 NFRKB RBM48 SETDB1 SNRPD3 STX1A TBC1D2B UNC119 UTP14A	4 interacting genes: GABARAPL1 MAP1LC3A MTDH TRDMT1
Entrez ID		1787	23102
HPRD ID		16001	08310
Ensembl ID		ENSG00000107614	ENSG00000167202
Uniprot IDs		B4DQZ2 O14717 Q6ICS7 Q7Z3E4	B2RTQ2 Q9UPU7
PDB IDs		1G55
Enriched GO Terms of Interacting Partners?			Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Mitophagy Autophagosome Maturation Autophagosome Membrane Autophagy Of Mitochondrion Autophagosome Autophagosome Assembly Autophagosome Organization Phospholipid Binding Protein-containing Complex Disassembly Macroautophagy TRNA (cytidine-5-)-methyltransferase Activity Vacuole Organization Cellular Response To Starvation Cellular Response To Oxygen-glucose Deprivation Response To Starvation TRNA Methyltransferase Activity TRNA Stabilization Cellular Response To Nutrient Levels Autophagy Ubiquitin Protein Ligase Binding Response To Iron(II) Ion Intercellular Canaliculus Microtubule Tat Protein Binding Response To Oxygen-glucose Deprivation Glycophagy Autolysosome GABA Receptor Binding Response To Lead Ion Response To Nutrient Levels Glycogen Catabolic Process Cellular Response To Copper Ion Polysaccharide Catabolic Process SMAD Protein Signal Transduction P38MAPK Cascade Response To Iron Ion NF-kappaB Binding Response To Copper Ion TRNA Methylation Lipopolysaccharide-mediated Signaling Pathway Beta-tubulin Binding Organelle Assembly Organelle Membrane
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