TRDMT1 and GBE1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TRDMT1	GBE1
Gene Name		tRNA aspartic acid methyltransferase 1	glucan (1,4-alpha-), branching enzyme 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytosol Extracellular Vesicular Exosome
	Molecular Function	DNA Binding RNA Binding DNA (cytosine-5-)-methyltransferase Activity TRNA Methyltransferase Activity	1,4-alpha-glucan Branching Enzyme Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Cation Binding
	Biological Process	Response To Amphetamine TRNA Methylation C-5 Methylation Of Cytosine	Carbohydrate Metabolic Process Glycogen Metabolic Process Glycogen Biosynthetic Process Glucose Metabolic Process Generation Of Precursor Metabolites And Energy Pathogenesis Small Molecule Metabolic Process
Pathways			Glucose metabolism Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: APP COPS6 DDX24 EEF1A1 GBE1 LRIF1 NFRKB RBM48 SETDB1 SNRPD3 STX1A TBC1D2B UNC119 UTP14A	4 interactors: EPHB3 PGD PRMT6 TRDMT1
Entrez ID		1787	2632
HPRD ID		16001	01985
Ensembl ID		ENSG00000107614	ENSG00000114480
Uniprot IDs		E7EMI8 O14717 Q6ICS7	E9PGM4 Q04446 Q59ET0
PDB IDs		1G55	4BZY
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-mediated Endocytosis MRNA 3'-end Processing Nucleobase-containing Compound Metabolic Process Negative Regulation Of Caveolin-mediated Endocytosis Synaptic Growth At Neuromuscular Junction Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA 3'-end Processing Collateral Sprouting In Absence Of Injury Cytokinesis, Completion Of Separation Cellular Nitrogen Compound Metabolic Process	D-gluconate Metabolic Process Histone H3-R2 Methylation Pentose-phosphate Shunt, Oxidative Branch Pentose Biosynthetic Process C-5 Methylation Of Cytosine Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Methylation DNA Methylation On Cytosine Dendritic Spine Morphogenesis Histone H4-R3 Methylation Peptidyl-arginine N-methylation Corpus Callosum Development Dendritic Spine Development Pentose-phosphate Shunt Dendritic Spine Organization Histone Arginine Methylation Retinal Ganglion Cell Axon Guidance Peptidyl-arginine Methylation Glyceraldehyde-3-phosphate Metabolic Process Regulation Of Rac GTPase Activity TRNA Methylation Axonal Fasciculation Regulation Of Cdc42 GTPase Activity Regulation Of Cdc42 Protein Signal Transduction Glucose 6-phosphate Metabolic Process Positive Regulation Of Synapse Assembly Response To Amphetamine NADP Metabolic Process Neuron Recognition Regulation Of Rac Protein Signal Transduction Central Nervous System Projection Neuron Axonogenesis Substrate Adhesion-dependent Cell Spreading
Tagcloud ?		a201g caucasian cpg description dnmt dnmt1 dnmt2 dnmt3a dnmt3b dnmts fisher genotyped gg homozygous hormonal hypermethylation hypomethylation islands loci methylate methyltransferases qpcr rs2228612 snp squared statistics tnm uses wildtype	amylopectin branching cardiomyocyte cardiomyocytes compaction contrary e609x expectations fetal fetalis glycogen gsd hearts hydrops hypertrabeculation lethality manifestation noncompaction osmotic pathogenetic polysaccharide presumably recapitulated recessive stop swelling trabeculation ventricular
Tagcloud (Difference) ?		a201g caucasian cpg description dnmt dnmt1 dnmt2 dnmt3a dnmt3b dnmts fisher genotyped gg homozygous hormonal hypermethylation hypomethylation islands loci methylate methyltransferases qpcr rs2228612 snp squared statistics tnm uses wildtype	amylopectin branching cardiomyocyte cardiomyocytes compaction contrary e609x expectations fetal fetalis glycogen gsd hearts hydrops hypertrabeculation lethality manifestation noncompaction osmotic pathogenetic polysaccharide presumably recapitulated recessive stop swelling trabeculation ventricular
Tagcloud (Intersection) ?