MYCBP and ARHGEF40

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MYCBP	ARHGEF40
Description		MYC binding protein	Rho guanine nucleotide exchange factor 40
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion	Cytoplasm Cytosol Plasma Membrane Extrinsic Component Of Membrane
	Molecular Function	Transcription Coactivator Activity Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Spermatogenesis Positive Regulation Of DNA-templated Transcription	Axon Guidance Regulation Of Small GTPase Mediated Signal Transduction
Pathways			NRAGE signals death through JNK G alpha (12/13) signalling events RHOA GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS		Beard thickness ( 26926045) Menopause (age at onset) ( 26414677)	Appendicular lean mass ( 33097823) Hematocrit ( 27863252 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Neuroblastoma (pediatric) ( 32599975) Pediatric nonalcoholic steatohepatitis ( 28918882) Plateletcrit ( 32888494) PR interval ( 32439900) Red blood cell count ( 32888494) Resting heart rate ( 27798624)
Interacting Genes		17 interacting genes: AKAP1 ARHGEF40 CFAP91 CFL1 COPS6 CPNE1 CPNE2 CPNE4 DISP3 ERBB3 GDF9 MYC MYCBPAP PTN SSRP1 UBC UBE3A	7 interacting genes: APP CBY2 GPSM2 MAPT MYCBP STC2 TAC1
Entrez ID		26292	55701
HPRD ID		08406	13335
Ensembl ID		ENSG00000214114	ENSG00000165801
Uniprot IDs		Q99417	Q8TER5
PDB IDs		2YY0
Enriched GO Terms of Interacting Partners?		Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway Calcium-dependent Phospholipid Binding Cellular Response To Calcium Ion Cofilin-actin Rod Regulation Of Developmental Process Negative Regulation Of Unidimensional Cell Growth Positive Regulation Of Establishment Of Cell Polarity Regulating Cell Shape Positive Regulation Of Barbed-end Actin Filament Capping Protein-containing Complex Disassembly Positive Regulation Of Protein Localization To Cell Leading Edge Regulation Of Epithelial Cell Proliferation Developmental Growth Protein-DNA Complex Disassembly Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Acinar Cell Proliferation Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Regulation Of Neuron Projection Regeneration Neuron Projection Regeneration Regulation Of Axon Regeneration Chondroitin Sulfate Proteoglycan Binding Sperm Entry Positive Regulation Of Golgi Lumen Acidification Cellular Response To Metal Ion Response To Calcium Ion Regulation Of Neuron Projection Development Positive Regulation Of Epithelial Cell Proliferation Regulation Of Synaptic Plasticity Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Neuron Projection Development Negative Regulation Of Postsynaptic Density Organization Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Female Gamete Generation Regulation Of Progesterone Secretion Myc-Max Complex Regulation Of Acinar Cell Proliferation Dendrite Regeneration Chemorepulsion Involved In Postnatal Olfactory Bulb Interneuron Migration Radial Spoke Stalk Developmental Process Involved In Reproduction	Response To Nerve Growth Factor Cellular Response To Nerve Growth Factor Stimulus Main Axon Antifungal Humoral Response Regulation Of Superoxide Anion Generation Apolipoprotein Binding Response To Lead Ion Response To Yeast Positive Regulation Of Supramolecular Fiber Organization Astrocyte Activation Neuronal Dense Core Vesicle Memory Positive Regulation Of Superoxide Anion Generation Negative Regulation Of Blood Circulation Positive Regulation Of Cytoskeleton Organization Amyloid Fibril Formation Regulation Of Superoxide Metabolic Process Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Regulation Of Microtubule-based Process Learning Or Memory Cellular Response To Growth Factor Stimulus Cognition Regulation Of Developmental Growth Response To Growth Factor Defense Response To Fungus Response To Fungus Macrophage Activation Antibacterial Humoral Response Amyloid-beta Complex Axon Growth Cone Lamellipodium Enzyme Binding Regulation Of Response To Calcium Ion Regulation Of Multicellular Organism Growth Amylin Binding Regulation Of Supramolecular Fiber Organization Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Reactive Oxygen Species Metabolic Process Histone-dependent DNA Binding Tubulin Complex Microtubule Lateral Binding Axo-dendritic Transport Cell Body Positive Regulation Of Cellular Component Organization Regulation Of Membrane Potential Positive Regulation Of Protein Localization Defense Response To Gram-negative Bacterium Regulation Of Calcium-mediated Signaling Associative Learning
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