MYCBP and CPNE1

Number of citations of the paper that reports this interaction (PubMedID 12522145)
0

Data Source:
HPRD (two hybrid, in vitro)

		MYCBP	CPNE1
Description		MYC binding protein	copine 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Nuclear Membrane Azurophil Granule Membrane Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity Protein Binding	Phosphatidylserine Binding Endopeptidase Activity Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Identical Protein Binding Metal Ion Binding NF-kappaB Binding
	Biological Process	Regulation Of DNA-templated Transcription Spermatogenesis Positive Regulation Of DNA-templated Transcription	Proteolysis Lipid Metabolic Process Negative Regulation Of Gene Expression Vesicle-mediated Transport Cell Differentiation Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of DNA Binding Positive Regulation Of Neuron Differentiation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Calcium Ion Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Neuron Projection Extension
Pathways			Glycerophospholipid biosynthesis Neutrophil degranulation
Drugs			Theophylline
Diseases
GWAS		Beard thickness ( 26926045) Menopause (age at onset) ( 26414677)	Blood protein levels ( 30072576) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		17 interacting genes: AKAP1 ARHGEF40 CFAP91 CFL1 COPS6 CPNE1 CPNE2 CPNE4 DISP3 ERBB3 GDF9 MYC MYCBPAP PTN SSRP1 UBC UBE3A	22 interacting genes: ACTB BCOR BUB3 CCDC22 CEBPA CPNE4 LHX6 LIG4 MAP2K1 MYCBP PDCD6 PITPNM2 PPP5C RDX SKIL SNCA SORBS3 SPTBN1 STK3 UBE2M UBE2O WTAP
Entrez ID		26292	8904
HPRD ID		08406	05014
Ensembl ID		ENSG00000214114	ENSG00000214078
Uniprot IDs		Q99417	B0QZ18 Q99829
PDB IDs		2YY0
Enriched GO Terms of Interacting Partners?		Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway Calcium-dependent Phospholipid Binding Cellular Response To Calcium Ion Cofilin-actin Rod Regulation Of Developmental Process Negative Regulation Of Unidimensional Cell Growth Positive Regulation Of Establishment Of Cell Polarity Regulating Cell Shape Positive Regulation Of Barbed-end Actin Filament Capping Protein-containing Complex Disassembly Positive Regulation Of Protein Localization To Cell Leading Edge Regulation Of Epithelial Cell Proliferation Developmental Growth Protein-DNA Complex Disassembly Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Acinar Cell Proliferation Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Regulation Of Neuron Projection Regeneration Neuron Projection Regeneration Regulation Of Axon Regeneration Chondroitin Sulfate Proteoglycan Binding Sperm Entry Positive Regulation Of Golgi Lumen Acidification Cellular Response To Metal Ion Response To Calcium Ion Regulation Of Neuron Projection Development Positive Regulation Of Epithelial Cell Proliferation Regulation Of Synaptic Plasticity Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Neuron Projection Development Negative Regulation Of Postsynaptic Density Organization Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Female Gamete Generation Regulation Of Progesterone Secretion Myc-Max Complex Regulation Of Acinar Cell Proliferation Dendrite Regeneration Chemorepulsion Involved In Postnatal Olfactory Bulb Interneuron Migration Radial Spoke Stalk Developmental Process Involved In Reproduction	Regulation Of Norepinephrine Uptake Cellular Response To Metal Ion Response To Metal Ion Transporter Regulator Activity Tau Protein Binding Regulation Of Protein Localization To Cell Periphery Protein-containing Complex Nucleus Regulation Of Organelle Organization Protein-containing Complex Binding Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Apical Protein Localization Cellular Response To Lithium Ion Magnesium Ion Binding Protein Domain Specific Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Response To Lithium Ion MAPK Cascade Regulation Of Early Endosome To Late Endosome Transport Structural Constituent Of Cytoskeleton Regulation Of Apoptotic Process Cytoskeleton Regulation Of Programmed Cell Death Nucleoplasm Regulation Of Cellular Component Organization Cortical Cytoskeleton Glutamatergic Synapse Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Catabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Receptor Localization To Synapse Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cell Differentiation Cell Development Regulation Of Signal Transduction Regulation Of Macromolecule Metabolic Process Positive Regulation Of Developmental Process Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Establishment Of Integrated Proviral Latency Central Nervous System Development Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Supramolecular Fiber Organization Actin Filament Capping Negative Regulation Of Actin Filament Depolymerization Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly
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