RSL1D1 and ADH6

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		RSL1D1	ADH6
Description		ribosomal L1 domain containing 1	alcohol dehydrogenase 6 (class V)
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Nucleolus Cytosol Cilium Membrane	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding Cadherin Binding MRNA 5'-UTR Binding	Alcohol Dehydrogenase (NAD+) Activity All-trans-retinol Dehydrogenase (NAD+) Activity Zinc Ion Binding Oxidoreductase Activity Metal Ion Binding
	Biological Process	Osteoblast Differentiation Regulation Of Protein Localization Regulation Of Apoptotic Process Regulation Of Cellular Senescence	Retinol Metabolic Process Retinoic Acid Metabolic Process
Pathways			Ethanol oxidation
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Testicular germ cell tumor ( 26503584 28604728 28604732)	Alcohol dependence ( 23456092) Alcohol use disorder (consumption score) ( 30336701 30940813) Alcohol use disorder (dependence and problematic use scores) ( 30336701) Aspartate aminotransferase levels ( 33547301) Esophageal cancer ( 19698717) QRS duration ( 23534349) Regular attendance at a pub or social club ( 29970889) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		12 interacting genes: ADARB1 ADH6 APP CAB39 CEBPA CSNK2A1 IL7R MDM2 PTEN TP53 USP25 USP7	8 interacting genes: ANKRD17 ARRB1 KRAS RASSF5 RPAIN RPS29 RSL1D1 TNIP1
Entrez ID		26156	130
HPRD ID		10897	00067
Ensembl ID		ENSG00000171490	ENSG00000172955
Uniprot IDs		O76021	P28332 Q8IUN7
PDB IDs		8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL2 8FL6 8FLA 8FLD 8INE 8INF 8IPX 8IPY 8IR3
Enriched GO Terms of Interacting Partners?		Regulation Of Proteolysis Response To Stress Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Regulation Of Protein Stability Regulation Of Proteasomal Protein Catabolic Process PML Body Positive Regulation Of Catabolic Process Regulation Of Signal Transduction By P53 Class Mediator Symbiont-mediated Disruption Of Host Cell PML Body Cellular Response To Actinomycin D Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle Regulation Of Cell Population Proliferation Response To Actinomycin D Intracellular Signal Transduction Cellular Response To UV-C Negative Regulation Of Macromolecule Metabolic Process Protein-containing Complex Regulation Of Biological Quality Positive Regulation Of Proteolysis Negative Regulation Of Metabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Apoptotic Process Negative Regulation Of Signal Transduction P53 Binding Programmed Cell Death Protein Stabilization Cell Death Regulation Of Cellular Response To Stress Negative Regulation Of Signaling Negative Regulation Of Cell Communication Cellular Response To Antibiotic Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Rhythmic Process Cytosol Cellular Response To Stress Signal Transduction Response To UV-C Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Identical Protein Binding Negative Regulation Of Protein Catabolic Process Negative Regulation Of Cell Cycle Negative Regulation Of Cell Population Proliferation Circadian Behavior Negative Regulation Of Catabolic Process	Regulation Of Post-translational Protein Modification Regulation Of Cellular Senescence Regulation Of Canonical NF-kappaB Signal Transduction Leukocyte Cell-cell Adhesion Leukocyte Adhesion To Arterial Endothelial Cell Mitochondrial Manganese Ion Transmembrane Transport Zinc:bicarbonate Symporter Activity Iron Ion Import Across Plasma Membrane Plasma Membrane Selenite Transport Mercury Ion Transport Positive Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Modification Process Angiotensin Receptor Binding Regulation Of Intracellular Signal Transduction Response To Isolation Stress GMP Binding Forebrain Astrocyte Development Negative Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Post-translational Protein Modification Positive Regulation Of MDA-5 Signaling Pathway Cellular Detoxification Of Cadmium Ion Monoatomic Cation:bicarbonate Symporter Activity Cartilage Homeostasis
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