ADH6 and RSL1D1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ADH6	RSL1D1
Gene Name		alcohol dehydrogenase 6 (class V)	ribosomal L1 domain containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Nucleolus Membrane
	Molecular Function	Alcohol Dehydrogenase (NAD) Activity Alcohol Dehydrogenase Activity, Zinc-dependent Zinc Ion Binding Ethanol Binding	Poly(A) RNA Binding
	Biological Process	Ethanol Oxidation Xenobiotic Metabolic Process Small Molecule Metabolic Process Response To Ethanol	Osteoblast Differentiation Regulation Of Protein Localization Regulation Of Apoptotic Process Regulation Of Cellular Senescence
Pathways		Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B) Defective FMO3 causes Trimethylaminuria (TMAU) Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD) Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR) Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX) Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4) Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA) Ethanol oxidation Metabolic disorders of biological oxidation enzymes Defective CYP1B1 causes Glaucoma Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A) Phase 1 - Functionalization of compounds Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5) Defective CYP19A1 causes Aromatase excess syndrome (AEXS) Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3) Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5) Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4) Defective CYP24A1 causes Hypercalcemia, infantile (HCAI) Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56) Defective MAOA causes Brunner syndrome (BRUNS) Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency) Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3) Biological oxidations
Drugs
Diseases
GWAS		Alcohol dependence ( 23456092) Esophageal cancer ( 19698717) QRS duration ( 23534349)
Protein-Protein Interactions		8 interactors: ANKRD17 ARRB1 KRAS RASSF5 RPAIN RPS29 RSL1D1 TNIP1	3 interactors: ADH6 CSNK2A1 IL7R
Entrez ID		130	26156
HPRD ID		00067	10897
Ensembl ID		ENSG00000172955	ENSG00000171490
Uniprot IDs		E9PBI1 P28332 Q8IUN7	O76021
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Ras Protein Signal Transduction Response To Light Stimulus Positive Regulation Of Small GTPase Mediated Signal Transduction Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Response To Radiation Regulation Of MAPK Cascade Positive Regulation Of Rac Protein Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of ERK1 And ERK2 Cascade Regulation Of Protein Localization Positive Regulation Of Intracellular Signal Transduction Regulation Of Protein Ubiquitination Positive Regulation Of MDA-5 Signaling Pathway Response To Stress Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Smooth Muscle Cell Differentiation Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Protein Modification Process Positive Regulation Of RIG-I Signaling Pathway	Interleukin-7-mediated Signaling Pathway Negative Regulation Of T Cell Mediated Cytotoxicity Negative Regulation Of T Cell Mediated Immunity Ethanol Oxidation Lymph Node Development Positive Regulation Of T Cell Differentiation In Thymus
Tagcloud ?		aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Difference) ?		aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Intersection) ?