ADH6 and RPS29

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ADH6	RPS29
Gene Name		alcohol dehydrogenase 6 (class V)	ribosomal protein S29
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Cytoplasm Cytosol Focal Adhesion Small Ribosomal Subunit Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Alcohol Dehydrogenase (NAD) Activity Alcohol Dehydrogenase Activity, Zinc-dependent Zinc Ion Binding Ethanol Binding	Structural Constituent Of Ribosome Zinc Ion Binding
	Biological Process	Ethanol Oxidation Xenobiotic Metabolic Process Small Molecule Metabolic Process Response To Ethanol	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B) Defective FMO3 causes Trimethylaminuria (TMAU) Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD) Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR) Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX) Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4) Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA) Ethanol oxidation Metabolic disorders of biological oxidation enzymes Defective CYP1B1 causes Glaucoma Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A) Phase 1 - Functionalization of compounds Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5) Defective CYP19A1 causes Aromatase excess syndrome (AEXS) Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3) Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5) Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4) Defective CYP24A1 causes Hypercalcemia, infantile (HCAI) Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56) Defective MAOA causes Brunner syndrome (BRUNS) Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency) Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3) Biological oxidations	Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Alcohol dependence ( 23456092) Esophageal cancer ( 19698717) QRS duration ( 23534349)	Post-traumatic stress disorder (asjusted for relatedness) ( 23726511) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Visceral fat ( 22589738)
Protein-Protein Interactions		8 interactors: ANKRD17 ARRB1 KRAS RASSF5 RPAIN RPS29 RSL1D1 TNIP1	4 interactors: ADH6 CTBP2 SMARCD1 UMPS
Entrez ID		130	6235
HPRD ID		00067	04698
Ensembl ID		ENSG00000172955	ENSG00000213741
Uniprot IDs		E9PBI1 P28332 Q8IUN7	P62273
PDB IDs			2ZKQ 3J3A
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Ras Protein Signal Transduction Response To Light Stimulus Positive Regulation Of Small GTPase Mediated Signal Transduction Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Response To Radiation Regulation Of MAPK Cascade Positive Regulation Of Rac Protein Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of ERK1 And ERK2 Cascade Regulation Of Protein Localization Positive Regulation Of Intracellular Signal Transduction Regulation Of Protein Ubiquitination Positive Regulation Of MDA-5 Signaling Pathway Response To Stress Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Smooth Muscle Cell Differentiation Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Protein Modification Process Positive Regulation Of RIG-I Signaling Pathway	'de Novo' UMP Biosynthetic Process Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Chromatin Binding 'de Novo' Pyrimidine Nucleobase Biosynthetic Process Chromatin-mediated Maintenance Of Transcription UMP Biosynthetic Process Ethanol Oxidation Nucleosome Disassembly White Fat Cell Differentiation Positive Regulation Of Gene Expression, Epigenetic Viral Genome Replication Pyrimidine Nucleobase Metabolic Process
Tagcloud ?		aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic	26s a2 carcinogenesis consistently cytochromosome detecting differentially dot dysplasia est etc expressions ferritin fragments gastric hybridization hypothetical mucosa oxidase proteasome rps12 screen semi ssh stages subtractive tags transcriptase verifying
Tagcloud (Difference) ?		aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic	26s a2 carcinogenesis consistently cytochromosome detecting differentially dot dysplasia est etc expressions ferritin fragments gastric hybridization hypothetical mucosa oxidase proteasome rps12 screen semi ssh stages subtractive tags transcriptase verifying
Tagcloud (Intersection) ?