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NOC2L and HIST2H2AA3
Number of citations of the paper that reports this interaction (PMID
16322561
)
17
Data Source:
BioGRID
(pull down)
NOC2L
HIST2H2AA3
Gene Name
nucleolar complex associated 2 homolog (S. cerevisiae)
histone cluster 2, H2aa3
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Nucleosome
Nucleus
Extracellular Vesicular Exosome
Molecular Function
Chromatin Binding
Transcription Corepressor Activity
Protein Binding
Nucleosome Binding
Histone Binding
Poly(A) RNA Binding
Repressing Transcription Factor Binding
Molecular_function
DNA Binding
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of B Cell Apoptotic Process
Transcription, DNA-templated
Apoptotic Process
Chromatin Assembly
Nucleolus To Nucleoplasm Transport
Cellular Response To UV
Negative Regulation Of Histone Acetylation
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Biological_process
Pathways
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
Deposition of new CENPA-containing nucleosomes at the centromere
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
Packaging Of Telomere Ends
Telomere Maintenance
Nucleosome assembly
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Meiotic synapsis
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
APP
ATN1
ATXN7
HIST2H2AA3
HIST2H2BA
HIST3H3
HIST4H4
LRIF1
PPP1CA
RBFOX1
16 interactors:
APP
BAP1
BMI1
DNAJC2
IL33
MSL2
NOC2L
PARP1
PRMT6
RCC1
RNF2
RNF20
TBL1X
UBE2H
USP16
USP21
Entrez ID
26155
8337
HPRD ID
13166
08851
Ensembl ID
ENSG00000188976
Uniprot IDs
Q9Y3T9
Q6FI13
PDB IDs
Enriched GO Terms of Interacting Partners
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Neuron Apoptotic Process
Nucleobase-containing Compound Metabolic Process
Neuron Death
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Telomere Maintenance
Regulation Of Gene Expression
Neuromuscular Process Controlling Balance
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Synaptic Growth At Neuromuscular Junction
Nitrogen Compound Metabolic Process
Neuromuscular Process
Collateral Sprouting In Absence Of Injury
Histone H4-K20 Demethylation
Negative Regulation Of Megakaryocyte Differentiation
Collateral Sprouting
Axon Midline Choice Point Recognition
Regulation Of RNA Metabolic Process
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axon Choice Point Recognition
Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
RNA Metabolic Process
Negative Regulation Of Hematopoietic Progenitor Cell Differentiation
Neuron Remodeling
DNA Replication-dependent Nucleosome Assembly
Regulation Of Glycogen Catabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Maintenance Of Cell Polarity
DNA Methylation On Cytosine
Toxin Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Chromosome Organization
Regulation Of Metabolic Process
Chromatin Silencing At RDNA
Cellular Metabolic Process
Chromosome Organization
Chromatin Organization
Chromatin Modification
Histone Modification
Organelle Organization
Histone Ubiquitination
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Cellular Protein Modification Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Cellular Protein Metabolic Process
Regulation Of RNA Biosynthetic Process
Gene Expression
Regulation Of RNA Metabolic Process
Histone Deubiquitination
Histone Monoubiquitination
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Histone H2A-K119 Monoubiquitination
Protein Metabolic Process
Protein Catabolic Process
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Nucleobase-containing Compound Metabolic Process
Monoubiquitinated Histone H2A Deubiquitination
Positive Regulation Of Gene Expression
Macromolecule Biosynthetic Process
Protein Monoubiquitination
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Cellular Macromolecule Catabolic Process
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