NOC2L

Description		NOC2 like nucleolar associated transcriptional repressor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Noc1p-Noc2p Complex Noc2p-Noc3p Complex
	Molecular Function	Chromatin Binding Transcription Corepressor Activity RNA Binding Protein Binding Nucleosome Binding Histone Binding DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of B Cell Apoptotic Process Apoptotic Process Cellular Response To UV Ribosomal Large Subunit Biogenesis Transcription Initiation-coupled Chromatin Remodeling Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Regulation of TP53 Activity through Phosphorylation
Drugs
Diseases
GWAS		California verbal learning test score ( 31596458) Pancreatic cancer ( 29422604)
Novel Interacting Genes		1 novel interacting genes: PTGFR
Interacting Genes		11 interacting genes: APP ATN1 ATXN7 H2AC18 H2BP1 H3-4 H4C16 LRIF1 PPP1CA RBFOX1 RNF10
Entrez ID		26155
HPRD ID		13166
Ensembl ID		ENSG00000188976
Uniprot IDs		Q9Y3T9
PDB IDs		8FKV 8FKW 8FKX 8FKY
Enriched GO Terms of Interacting Partners?		Chromosome, Telomeric Region Chromatin Remodeling Response To Lead Ion Transition Metal Ion Binding Protein Heterodimerization Activity Nucleosome Structural Constituent Of Chromatin Nuclear Matrix Chromatin Organization Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Epigenetic Regulation Of Gene Expression Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Gene Expression Positive Regulation Of Toll Signaling Pathway Prostaglandin F Receptor Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of Carbohydrate Catabolic Process Chromosome Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Nucleus PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Regulation Of Spontaneous Synaptic Transmission Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Macromolecule Metabolic Process Regulation Of Synapse Structure Or Activity Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Regulation Of Toll Signaling Pathway Growth Factor Receptor Binding
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