ANKRD17 and ECPAS

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		ANKRD17	ECPAS
Description		ankyrin repeat domain 17	Ecm29 proteasome adaptor and scaffold
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Membrane	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Trans-Golgi Network Centrosome Cytoskeleton Membrane COPII-coated ER To Golgi Transport Vesicle Endocytic Vesicle Cytoplasmic Vesicle
	Molecular Function	Nucleic Acid Binding Chromatin Binding RNA Binding Protein Binding	Protein Binding Molecular Adaptor Activity Proteasome Binding
	Biological Process	Immune System Process Regulation Of DNA Replication Defense Response To Bacterium Positive Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Positive Regulation Of Cell Cycle Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway	ERAD Pathway Proteasome Assembly
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Cholesterol ester levels in large LDL ( 29084231) Cholesterol ester levels in medium LDL ( 29084231) Esterified cholesterol levels ( 29084231) Free cholesterol levels in large LDL ( 29084231) Hematocrit ( 32888494) Large LDL particle concentration ( 29084231) Medium LDL particle concentration ( 29084231) Prostate cancer ( 23535732) Red blood cell count ( 32888494) Smooth-surface caries ( 24556642) Total cholesterol levels in large LDL ( 29084231) Total cholesterol levels in medium LDL ( 29084231) Total cholesterol levels in small LDL ( 29084231)
Interacting Genes		6 interacting genes: ADH6 APC ECPAS ITSN2 MDM2 RNF10	36 interacting genes: AGTRAP ANK2 ANKRD17 BSND CCDC57 CEBPA CEP170B CKS1B CMTM5 CMTM6 CPD DGAT2L6 DNAJB9 DST FBXO2 GAREM2 GOLGB1 HNRNPM HSD17B13 HSPB1 MAL2 MKI67 MYH10 PCM1 PCYT1B RAB11FIP4 RNF168 SF3B2 SPECC1L SYNE1 TNFRSF10D UBE2G2 UBE2Q1 UIMC1 VPS11 ZNF483
Entrez ID		26057	23392
HPRD ID		10648	11078
Ensembl ID		ENSG00000132466	ENSG00000136813
Uniprot IDs		O75179	A0AAA9X0G7 Q5VYK3
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Catabolic Process Heart Valve Development Proteolysis Involved In Protein Catabolic Process Proteasomal Protein Catabolic Process Endocardial Cushion Morphogenesis Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Proteolysis Response To Formaldehyde Cellular Response To Vitamin B1 Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Clathrin-dependent Synaptic Vesicle Endocytosis Centrosome Response To Vitamin B1 Response To Water-immersion Restraint Stress Cellular Response To Actinomycin D Regulation Of G1/S Transition Of Mitotic Cell Cycle NEDD8 Ligase Activity Response To Actinomycin D Traversing Start Control Point Of Mitotic Cell Cycle Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To UV-C Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane Catabolic Process Receptor Serine/threonine Kinase Binding Positive Regulation Of Protein Catabolic Process Positive Regulation Of Protein Localization To Centrosome Alcohol Dehydrogenase (NAD+) Activity Leading Edge Membrane Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Atrial Septum Development Fibroblast Activation Peroxisome Proliferator Activated Receptor Binding Cellular Response To Antibiotic 5S RRNA Binding Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Schwann Cell Proliferation
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