ZNF451 and RNF40

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZNF451	RNF40
Gene Name		zinc finger protein 451	ring finger protein 40, E3 ubiquitin protein ligase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Ubiquitin Ligase Complex Nucleus Nucleoplasm Membrane HULC Complex Neuron Projection
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Syntaxin-1 Binding Ubiquitin Protein Ligase Binding Protein Complex Binding Protein Homodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Ubiquitin-dependent Protein Catabolic Process Histone Monoubiquitination Histone H2B Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: AR CALCOCO2 CDC5L CPTP CREB1 FXR2 HTT JMJD6 KDM1A LZTR1 PCBD1 PIAS1 PIAS2 PRMT1 PRMT8 PRPF40A RAP1GDS1 RNF40 SNIP1 SUMO1 SUV39H1 UBC UBE2I	18 interactors: AMOTL2 ATM CCDC146 CDC73 HIST2H2BE ITSN1 MSL1 NCBP1 RB1 SFR1 TRIM51 UBE2A UBE2B UBE2E1 UBE2I UBE2L6 WAC ZNF451
Entrez ID		26036	9810
HPRD ID		10332	07411
Ensembl ID		ENSG00000112200	ENSG00000103549
Uniprot IDs		B4DYS2 Q96JY2 Q9Y4E5	A8K6K1 F8W8Z4 O75150
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Protein Sumoylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Peptidyl-lysine Modification Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Histone Modification Peptidyl-amino Acid Modification Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Androgen Receptor Signaling Pathway Organelle Organization RNA Metabolic Process Cellular Protein Modification Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Chromatin Modification Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Protein Modification By Small Protein Conjugation Heterocycle Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Intracellular Receptor Signaling Pathway Cellular Nitrogen Compound Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Chromatin Organization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Peptidyl-arginine N-methylation Nucleobase-containing Compound Metabolic Process Histone H4-R3 Methylation Regulation Of Innate Immune Response Diencephalon Development Regulation Of Binding Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Metabolic Process Histone Arginine Methylation Viral Process Peptidyl-arginine Methylation Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Rhythmic Process Regulation Of Transcription From RNA Polymerase II Promoter	Histone Ubiquitination Chromatin Organization Chromatin Modification Histone Modification Chromosome Organization Protein Monoubiquitination Histone H2B Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Histone Monoubiquitination Cellular Macromolecule Catabolic Process Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Metaphase/anaphase Transition ISG15-protein Conjugation Organelle Organization Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Cell Cycle Cell Cycle Checkpoint Regulation Of Cell Cycle Phase Transition Modification-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Division Proteasomal Protein Catabolic Process Regulation Of Chromosome Segregation Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Negative Regulation Of Chromosome Organization Cell Cycle Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Histone H2A Ubiquitination Positive Regulation Of MRNA 3'-end Processing Regulation Of MRNA 3'-end Processing Negative Regulation Of Protein Catabolic Process Cellular Protein Modification Process Regulation Of Mitotic Nuclear Division Catabolic Process Histone MRNA Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Postreplication Repair
Tagcloud ?		acetylation acts attenuates beta blocks bodies causes cofactor corepressor demonstrating depletion enhances functionally h3k9 inhibits interacts localized mechanistically negatively physically promoters promyelocytic recruit regulates responses smad3 taken tgf transcriptional	accessible alongside attracting deubiquitinases discoveries disrupt e3 fostering h2b h2bub1 h3k4 h3k79 ligases marking monoubiquitination parathyroid polyubiquitination ptm ptms recruiting rnf20 shed strands talk traditionally usp22 usp44 usp7 viewed
Tagcloud (Difference) ?		acetylation acts attenuates beta blocks bodies causes cofactor corepressor demonstrating depletion enhances functionally h3k9 inhibits interacts localized mechanistically negatively physically promoters promyelocytic recruit regulates responses smad3 taken tgf transcriptional	accessible alongside attracting deubiquitinases discoveries disrupt e3 fostering h2b h2bub1 h3k4 h3k79 ligases marking monoubiquitination parathyroid polyubiquitination ptm ptms recruiting rnf20 shed strands talk traditionally usp22 usp44 usp7 viewed
Tagcloud (Intersection) ?