ZNF451 and ZNF467

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF451	ZNF467
Description		zinc finger protein 451	zinc finger protein 467
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm PML Body	Nucleus
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Activity Protein Binding Zinc Ion Binding Transferase Activity Sequence-specific DNA Binding Metal Ion Binding SUMO Ligase Activity Transcription Regulator Inhibitor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Protein Sumoylation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transcription Initiation By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			Metabolite levels ( 31628463) Pulse pressure ( 30224653)
Interacting Genes		36 interacting genes: AR CALCOCO2 CBS CDC5L CDCA4 CPTP CREB1 CREBBP FAM118A FXR2 HTT JMJD6 KDM1A KLHL40 LZTR1 MID2 OPLAH PCBD1 PIAS1 PIAS2 PIK3R3 PML PRMT1 PRMT8 PRPF40A RAP1GDS1 RNF40 SNIP1 SUMO1 SUMO2 SUMO3 SUV39H1 UBC UBE2I ZBED1 ZNF467	8 interacting genes: KRTAP12-3 L3MBTL2 LMO4 STAT1 STAT3 STAT4 TLE5 ZNF451
Entrez ID		26036	168544
HPRD ID		10332	18343
Ensembl ID		ENSG00000112200	ENSG00000181444
Uniprot IDs		B4DYS2 Q96JY2 Q9Y4E5	C9JAX3 Q7Z7K2
PDB IDs		5D2M
Enriched GO Terms of Interacting Partners?		Protein Sumoylation PML Body SUMO Transferase Activity Protein Modification Process Presynaptic Cytosol Postsynaptic Cytosol Enzyme Binding Post-translational Protein Modification Protein Modification By Small Protein Conjugation Nucleus Protein Tag Activity Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Metabolic Process Ubiquitin Protein Ligase Binding Protein Metabolic Process Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Identical Protein Binding Positive Regulation Of RNA Metabolic Process Transcription Coactivator Activity SUMO Ligase Activity Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Primary Metabolic Process S-adenosyl-L-methionine Binding Positive Regulation Of Catabolic Process Ubiquitin-like Protein Ligase Binding Protein Demethylase Activity Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process MRF Binding Protein-arginine Omega-N Monomethyltransferase Activity Peptidyl-arginine Methylation Small Protein Activating Enzyme Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Histone Methyltransferase Activity Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Macromolecule Biosynthetic Process	RNA Polymerase II Transcription Regulator Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cell Surface Receptor Signaling Pathway Via STAT Cell Surface Receptor Signaling Pathway Via JAK-STAT Interleukin-9-mediated Signaling Pathway CCR5 Chemokine Receptor Binding Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Response To Cytokine Response To Peptide Regulation Of RNA Metabolic Process Transcription Corepressor Activity Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Erythrocyte Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Regulation Of Erythrocyte Differentiation Response To Peptide Hormone Negative Regulation Of Metabolic Process Identical Protein Binding Promoter-specific Chromatin Binding Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Regulation Of Gene Expression Cytokine-mediated Signaling Pathway Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of Nephron Tubule Epithelial Cell Differentiation Negative Regulation By Virus Of Viral Protein Levels In Host Cell DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Negative Regulation Of Canonical NF-kappaB Signal Transduction Sequence-specific DNA Binding Positive Regulation Of Myeloid Cell Differentiation Metanephric Mesenchymal Cell Proliferation Involved In Metanephros Development ISGF3 Complex Negative Regulation Of Primary MiRNA Processing Negative Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Skeletal Muscle Cell Proliferation Ventral Spinal Cord Interneuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Cell Differentiation Negative Regulation Of Epithelial Cell Differentiation Involved In Kidney Development
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