NSMF and CCDC125

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NSMF	CCDC125
Description		NMDA receptor synaptonuclear signaling and neuronal migration factor	coiled-coil domain containing 125
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Euchromatin Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Cell Cortex Postsynaptic Density Membrane Nuclear Matrix Dendrite Cortical Cytoskeleton Nuclear Membrane Cell Projection Neuron Projection Perikaryon Synapse Apical Dendrite	Cytoplasm
	Molecular Function	Protein Binding Calcium-dependent Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Neuron Apoptotic Process Regulation Of Neuronal Synaptic Plasticity Regulation Of Dendrite Morphogenesis Cellular Response To Amino Acid Stimulus Cellular Response To Electrical Stimulus Cellular Response To Gonadotropin Stimulus Regulation Of Neuron Migration Positive Regulation Of Neuron Migration	Negative Regulation Of Rho Protein Signal Transduction Activation Of GTPase Activity Regulation Of Cell Motility Negative Regulation Of Cell Motility
Pathways
Drugs
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS			Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252 32888494) Neutrophil percentage of white cells ( 27863252 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 27863252 32888494)
Interacting Genes		24 interacting genes: CALM1 CALM2 CALM3 CCDC125 CCNDBP1 GFI1B GOLGA2 GOLGA6L9 HSF2BP HSPB3 INTS11 KIFC3 LMO2 LXN MID2 MYL12B PNMA1 PTPN21 RAN SOCS7 TFIP11 TRIP6 UBASH3A VPS26C	64 interacting genes: AIRIM ATOSB BMP7 C21orf58 C22orf15 CCNG1 CDC23 CDK18 CEP95 DRC4 EIF3D FAM107A FAM161A FAM161B FAM47B FLYWCH1 GEM HAPLN2 HDAC4 KAT5 KIF9 KRTAP13-2 LCE2C MYH1 NEBL NSD1 NSMF OTOS PKP2 PRPF3 PTPA RAB2A RIPOR3 SFN SNW1 SPMIP2 STX11 TCHP TEAD4 TRIM14 TSGA10IP UACA YWHAE YWHAH YWHAQ YWHAZ ZFP1 ZFYVE26 ZNF165 ZNF230 ZNF250 ZNF32 ZNF337 ZNF343 ZNF417 ZNF436 ZNF552 ZNF557 ZNF564 ZNF587 ZNF764 ZNF792 ZNF837 ZNF883
Entrez ID		26012	202243
HPRD ID		10485	13774
Ensembl ID		ENSG00000165802	ENSG00000183323
Uniprot IDs		A8K7L5 Q6X4W1	B4DSR1 Q2HJ12 Q86Z20
PDB IDs
Enriched GO Terms of Interacting Partners?		Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Titin Binding Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calyx Of Held Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Transporter Activity Calcium Channel Complex Calcineurin-mediated Signaling Presynaptic Cytosol Myelin Sheath Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Calcium Ion Transmembrane Transport Spindle Microtubule Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Presynaptic Endocytosis Substantia Nigra Development Calcium Channel Regulator Activity Positive Regulation Of Sequestering Of Calcium Ion Sperm Midpiece Negative Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Long-term Synaptic Potentiation Cell Cycle G2/M Phase Transition Cytoplasm Sarcomere Spindle Pole Importin-alpha Family Protein Binding Neural Nucleus Development Adenylate Cyclase Binding Negative Regulation Of Cation Transmembrane Transport Protein Serine/threonine Kinase Activator Activity Negative Regulation Of Monoatomic Ion Transmembrane Transport Calcium Channel Inhibitor Activity Voltage-gated Potassium Channel Complex Regulation Of Voltage-gated Calcium Channel Activity Calcium-dependent Protein Binding Regulation Of Cardiac Muscle Contraction Regulation Of Release Of Sequestered Calcium Ion Into Cytosol	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Phosphoserine Residue Binding Zinc Ion Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus DNA Binding Transmembrane Transporter Binding
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