CCDC125 and MYH1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC125	MYH1
Description		coiled-coil domain containing 125	myosin heavy chain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Muscle Myosin Complex Intercalated Disc Myosin Complex Myosin II Complex Myofibril A Band Myosin Filament Cytoplasmic Ribonucleoprotein Granule Supramolecular Fiber
	Molecular Function	Protein Binding Identical Protein Binding	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Rho Protein Signal Transduction Activation Of GTPase Activity Regulation Of Cell Motility Negative Regulation Of Cell Motility	Muscle Contraction Sensory Perception Of Sound
Pathways
Drugs
Diseases
GWAS		Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252 32888494) Neutrophil percentage of white cells ( 27863252 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 27863252 32888494)
Interacting Genes		64 interacting genes: AIRIM ATOSB BMP7 C21orf58 C22orf15 CCNG1 CDC23 CDK18 CEP95 DRC4 EIF3D FAM107A FAM161A FAM161B FAM47B FLYWCH1 GEM HAPLN2 HDAC4 KAT5 KIF9 KRTAP13-2 LCE2C MYH1 NEBL NSD1 NSMF OTOS PKP2 PRPF3 PTPA RAB2A RIPOR3 SFN SNW1 SPMIP2 STX11 TCHP TEAD4 TRIM14 TSGA10IP UACA YWHAE YWHAH YWHAQ YWHAZ ZFP1 ZFYVE26 ZNF165 ZNF230 ZNF250 ZNF32 ZNF337 ZNF343 ZNF417 ZNF436 ZNF552 ZNF557 ZNF564 ZNF587 ZNF764 ZNF792 ZNF837 ZNF883	3 interacting genes: CCDC125 KRT13 STAU1
Entrez ID		202243	4619
HPRD ID		13774	08872
Ensembl ID		ENSG00000183323	ENSG00000109061
Uniprot IDs		B4DSR1 Q2HJ12 Q86Z20	P12882
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Phosphoserine Residue Binding Zinc Ion Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus DNA Binding Transmembrane Transporter Binding	Anterograde Dendritic Transport Of Messenger Ribonucleoprotein Complex LncRNA-mediated Post-transcriptional Gene Silencing Positive Regulation By Virus Of Viral Protein Levels In Host Cell Regulation Of Translation In Response To Stress Post-transcriptional Regulation Of Gene Expression Modification Of Postsynaptic Structure Dendritic Transport Protein Phosphatase 1 Binding Positive Regulation Of Long-term Synaptic Potentiation Anterograde Dendritic Transport Dendrite Cytoplasm Modification Of Synaptic Structure Intracellular MRNA Localization Activation Of GTPase Activity Negative Regulation Of Rho Protein Signal Transduction Positive Regulation Of Viral Genome Replication RNA Localization
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