CCDC125 and ZNF436

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC125	ZNF436
Description		coiled-coil domain containing 125	zinc finger protein 436
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Rho Protein Signal Transduction Activation Of GTPase Activity Regulation Of Cell Motility Negative Regulation Of Cell Motility	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252 32888494) Neutrophil percentage of white cells ( 27863252 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 27863252 32888494)	A body shape index ( 34021172) Estimated glomerular filtration rate ( 30604766 31015462) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 30598549) Waist-hip index ( 34021172)
Interacting Genes		64 interacting genes: AIRIM ATOSB BMP7 C21orf58 C22orf15 CCNG1 CDC23 CDK18 CEP95 DRC4 EIF3D FAM107A FAM161A FAM161B FAM47B FLYWCH1 GEM HAPLN2 HDAC4 KAT5 KIF9 KRTAP13-2 LCE2C MYH1 NEBL NSD1 NSMF OTOS PKP2 PRPF3 PTPA RAB2A RIPOR3 SFN SNW1 SPMIP2 STX11 TCHP TEAD4 TRIM14 TSGA10IP UACA YWHAE YWHAH YWHAQ YWHAZ ZFP1 ZFYVE26 ZNF165 ZNF230 ZNF250 ZNF32 ZNF337 ZNF343 ZNF417 ZNF436 ZNF552 ZNF557 ZNF564 ZNF587 ZNF764 ZNF792 ZNF837 ZNF883	14 interacting genes: CCDC125 CCDC57 CLK2 CREB1 KDM1A KIF9 NTAQ1 OGT PRMT5 PRMT6 SUV39H1 TRIM55 TRIM63 ZNF580
Entrez ID		202243	80818
HPRD ID		13774	15793
Ensembl ID		ENSG00000183323	ENSG00000125945
Uniprot IDs		B4DSR1 Q2HJ12 Q86Z20	A0AAA9YHR6 Q9C0F3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Phosphoserine Residue Binding Zinc Ion Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus DNA Binding Transmembrane Transporter Binding	Circadian Rhythm Histone Methyltransferase Activity Histone H3 Methyltransferase Activity Histone Arginine N-methyltransferase Activity Histone H4R3 Methyltransferase Activity Protein Modification Process Regulation Of Transcription By Glucose Protein-arginine N-methyltransferase Activity Rhythmic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Small Molecule Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Transferase Activity Identical Protein Binding Histone Methyltransferase Complex Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Methyltransferase Activity Chromatin Organization Negative Regulation Of RNA Metabolic Process Methylation Negative Regulation Of Metabolic Process Regulation Of Gluconeogenesis Protein Metabolic Process Regulation Of Multicellular Organismal Process Chemotaxis To Arachidonate Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Glycolytic Process Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Protein-N-terminal Glutamine Amidohydrolase Activity Histone H2AR3 Methyltransferase Activity Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Cardiac Muscle Tissue Development Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of Multicellular Organism Growth Chromatin Remodeling Epigenetic Regulation Of Gene Expression Circadian Regulation Of Gene Expression Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Carbohydrate Catabolic Process P53 Binding Peptidyl-arginine N-methylation Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Protein-N-terminal Asparagine Amidohydrolase Activity Histone H3R2 Methyltransferase Activity Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of ATP Metabolic Process
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