PNKD and KCTD9

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PNKD	KCTD9
Description		PNKD metallo-beta-lactamase domain containing	potassium channel tetramerization domain containing 9
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Membrane Presynaptic Cytosol
	Molecular Function	Hydroxyacylglutathione Hydrolase Activity Protein Binding Hydrolase Activity Metal Ion Binding	Protein Binding Identical Protein Binding Cullin Family Protein Binding
	Biological Process	Methylglyoxal Catabolic Process To D-lactate Via S-lactoyl-glutathione Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Dopamine Metabolic Process Negative Regulation Of Neurotransmitter Secretion Neuromuscular Process Controlling Posture	Protein Ubiquitination Intracellular Signal Transduction Protein Homooligomerization
Pathways
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS		Appendicular lean mass ( 33097823) Colorectal cancer ( 28960316) Colorectal cancer or advanced adenoma ( 30510241) Glycated hemoglobin levels ( 34059833) Granulocyte count ( 27863252) Height ( 28552196) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 23128233 28067908) Liver enzyme levels (alkaline phosphatase) ( 33972514) Monocyte count ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Plateletcrit ( 32888494 27863252) Red cell distribution width ( 28957414 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systolic blood pressure ( 30578418) Triglyceride levels ( 32203549) White blood cell count ( 27863252)	Lymphocyte count ( 32888494)
Interacting Genes		7 interacting genes: APP ENO3 KCTD9 KLHL20 MAGEA11 MYL12B UBC	91 interacting genes: ACTMAP ADAMTSL4 ANKS1A AQP1 ARID5A BANP BLZF1 CARD9 CBX8 CCDC33 CDC37 CDPF1 CFP CRADD DDIT4L DEUP1 EHHADH EPM2AIP1 FAM124B GEM GOLGA6L9 GORASP2 GPANK1 HOXA1 HOXC8 IGFN1 IL16 INCA1 KIF9 KLHL26 KRT31 KRT34 KRT35 KRT40 KRTAP13-2 KRTAP13-3 LNX1 LONRF1 MAD2L2 MBD3L1 MEOX2 MIIP MVP NDUFAB1 NIF3L1 NTAQ1 PDZD4 PFDN5 PICK1 PLOD3 PNKD POF1B PPP1R16B PPP1R18 PRDM6 PRKAA2 PSMA1 PSMB2 RBPMS RFX6 RUSC1 SAXO4 SDCBP SKP1 SLAIN1 SMARCB1 SMUG1 SPATS1 SPG21 SPMIP4 SPMIP6 SPMIP9 STX11 SYT6 TASOR2 TEPSIN TNS2 TRIM27 TRIM32 TRIM42 TRIP6 UNKL USP21 USP54 WDR83 ZBTB25 ZBTB42 ZNF408 ZNF426 ZNF620 ZNF76
Entrez ID		25953	54793
HPRD ID		11369	13772
Ensembl ID		ENSG00000127838	ENSG00000104756
Uniprot IDs		Q8N490	Q7L273
PDB IDs			5BXH
Enriched GO Terms of Interacting Partners?			Protein Binding Identical Protein Binding
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